| Literature DB >> 23955936 |
Cheng Zheng1, Xiao-Long Zhang, Wei Liu, Bo Liu, Huang-Hao Yang, Zi-An Lin, Guo-Nan Chen.
Abstract
A novel and general strategy is developed to design selective artificial enzyme inhibitor based on nanoparticleenzyme inter actions and molecular imprinting. Due to the creation of specific binding cavities, the resulting artificial inhibitor has high inhibition efficiency for the target enzyme, and shows great target-selectivity over other enzymes of similar function and proteins of compaable mole cular weight.Keywords: enzyme inhibitor; molecular imprinted polymers; molecular recognition; nanoparticles
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Year: 2013 PMID： 23955936 DOI： 10.1002/adma.201302064
Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849