Literature DB >> 23955359

[Lipid lowering therapy in geriatric patients].

M Lechleitner1.   

Abstract

Cardiovascular disease is also the most frequent cause of mortality in the elderly population. Invasive diagnostic and therapeutic interventions are performed at an increasing rate in older patients in order to maintain functional capacities and, thus, an adequate quality of life. Thus, strategies to prevent cardiovascular events (e.g., lipid lowering therapy) are also of great importance in elderly. With respect to the side effects of statin therapy, the risk of drug interaction has to be considered, as well as myopathy. Discrepant study results exist about the influence of statins on cognitive function. Retrospective analyses indicate that statin therapy might be related to an increased risk for type.2 diabetes in certain risk groups. The indication for statin therapy should, therefore, consider the risk profile and especially the individual situation of the older patient.

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Year:  2013        PMID: 23955359     DOI: 10.1007/s00391-013-0516-6

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  65 in total

1.  Treatment with drugs to lower blood pressure and blood cholesterol based on an individual's absolute cardiovascular risk.

Authors:  Rod Jackson; Carlene M M Lawes; Derrick A Bennett; Richard J Milne; Anthony Rodgers
Journal:  Lancet       Date:  2005 Jan 29-Feb 4       Impact factor: 79.321

2.  Reduced risk of incident AD with elective statin use in a clinical trial cohort.

Authors:  D Larry Sparks; Richard J Kryscio; Marwan N Sabbagh; Donald J Connor; Lisa M Sparks; Carolyn Liebsack
Journal:  Curr Alzheimer Res       Date:  2008-08       Impact factor: 3.498

3.  Delirium after elective surgery among elderly patients taking statins.

Authors:  Donald A Redelmeier; Deva Thiruchelvam; Nick Daneman
Journal:  CMAJ       Date:  2008-09-23       Impact factor: 8.262

4.  Total, LDL, and HDL cholesterol decrease with age in older men and women. The Rancho Bernardo Study 1984-1994.

Authors:  A Ferrara; E Barrett-Connor; J Shan
Journal:  Circulation       Date:  1997-07-01       Impact factor: 29.690

5.  Characteristics of Framingham offspring participants with long-lived parents.

Authors:  Dellara F Terry; Jane C Evans; Michael J Pencina; Joanne M Murabito; Ramachandran S Vasan; Philip A Wolf; Margaret Kelly-Hayes; Daniel Levy; Ralph B D'Agostino; Emelia J Benjamin
Journal:  Arch Intern Med       Date:  2007-03-12

6.  Statins and the risk of dementia.

Authors:  H Jick; G L Zornberg; S S Jick; S Seshadri; D A Drachman
Journal:  Lancet       Date:  2000-11-11       Impact factor: 79.321

7.  The prognostic significance of malnutrition as assessed by the Mini Nutritional Assessment (MNA) in older hospitalized patients with a heavy disease burden.

Authors:  Ulrich M Vischer; Emilia Frangos; Christophe Graf; Gabriel Gold; Lucien Weiss; François R Herrmann; Dina Zekry
Journal:  Clin Nutr       Date:  2011-10-11       Impact factor: 7.324

Review 8.  Management of cardiovascular risk: the importance of meeting lipid targets.

Authors:  Antonio M Gotto; Jennifer E Moon
Journal:  Am J Cardiol       Date:  2012-07-01       Impact factor: 2.778

9.  High-density vs low-density lipoprotein cholesterol as the risk factor for coronary artery disease and stroke in old age.

Authors:  Annelies W E Weverling-Rijnsburger; Iris J A M Jonkers; Eric van Exel; Jacobijn Gussekloo; Rudi G J Westendorp
Journal:  Arch Intern Med       Date:  2003-07-14

10.  Long-term fatal outcomes in subjects with stroke or transient ischemic attack: fourteen-year follow-up of the systolic hypertension in the elderly program.

Authors:  Alpesh B Patel; John B Kostis; Alan C Wilson; Michael L Shea; Sara L Pressel; Barry R Davis
Journal:  Stroke       Date:  2008-02-28       Impact factor: 7.914

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