Literature DB >> 23953711

Polymorphism in cathelicidin gene (CAMP) that alters Hypoxia-inducible factor (HIF-1α::ARNT) binding is not associated with tuberculosis.

G N López Campos1, J S Velarde Félix, L Sandoval Ramírez, S Cázares Salazar, A L Corona Nakamura, G Amaya Tapia, E Prado Montes de Oca.   

Abstract

Polymorphisms in the CAMP gene (cathelicidin) have not been tested in tuberculosis susceptibility. We tested polymorphisms rs9844812 (HIF-1α::ARNT binding site) and rs56122065 (CAMP) plus rs1800972 (DEFB1). SNP rs1800972 was associated with extrapulmonary tuberculosis (EPTB) in a codominant model (genotype CG, P = 0.037, OR 4.82; 95% CI: 0.92-47.42; statistical power, 82%), but not PTB (P = 0.101) in a Mexican population.
© 2013 John Wiley & Sons Ltd.

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Year:  2013        PMID: 23953711     DOI: 10.1111/iji.12080

Source DB:  PubMed          Journal:  Int J Immunogenet        ISSN: 1744-3121            Impact factor:   1.466


  4 in total

1.  Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatum.

Authors:  Roger A Fecher; Michael C Horwath; Dirk Friedrich; Jan Rupp; George S Deepe
Journal:  J Immunol       Date:  2016-06-06       Impact factor: 5.422

2.  Impact of Hypoxia on Drug Resistance and Growth Characteristics of Mycobacterium tuberculosis Clinical Isolates.

Authors:  Zhonghua Liu; Yulu Gao; Hua Yang; Haiyang Bao; Lianhua Qin; Changtai Zhu; Yawen Chen; Zhongyi Hu
Journal:  PLoS One       Date:  2016-11-11       Impact factor: 3.240

3.  Genetic diversity of Japanese quail cathelicidins.

Authors:  Taichiro Ishige; Hiromi Hara; Takashi Hirano; Tomohiro Kono; Kei Hanzawa
Journal:  Poult Sci       Date:  2021-02-27       Impact factor: 3.352

4.  DEFB1 gene polymorphisms and tuberculosis in a Northeastern Brazilian population.

Authors:  Ronaldo Celerino da Silva; Heidi Lacerda Alves da Cruz; Lucas André Cavalcanti Brandão; Rafael Lima Guimarães; Lilian Maria Lapa Montenegro; Haiana Charifker Schindler; Ludovica Segat; Sergio Crovella
Journal:  Braz J Microbiol       Date:  2016-03-02       Impact factor: 2.476

  4 in total

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