BACKGROUND AND OBJECTIVES: The goal of methadone maintenance treatment (MMT) is to reduce the harm and to improve patients' quality of life (Qol). However, the Qol is also influenced by other co-occurring disorders. Data regarding the Qol and the co-occurrence of these disorders is lacking in low-middle income countries. We therefore describe the prevalence of physical, psychiatric, and drug abuse co-occurring disorders among MMT patients in Indonesia and determine the association between the severity of the co-occurring disorders and the Qol. METHODS: Data were collected in 112 injection drug abusers (IDUs) attending a MMT program in West Java, Indonesia, using validated questionnaires, medical records and laboratory testing. For comparison, 154 IDUs not enrolled in MMT were recruited by respondent driven sampling. RESULTS: The most frequent co-occurring disorders were hepatitis C (92%), HIV (77%), benzodiazepine abuse (56%), and anxiety disorders (32%). IDUs in MMT had one (26%), two (47%), or three (27%) co-occurring disorders. Higher severity in psychiatric and physical problems was associated with poorer Qol. IDUs not enrolled in MMT had similar co-occurring problems. CONCLUSIONS: The prevalence of co-occurring disorders in IDUs in Indonesia is high and they influence their Qol. SCIENTIFIC SIGNIFICANCE: Therefore, comprehensive treatment, especially focusing on the common co-occurring disorders should be provided in MMT to improve the Qol.
BACKGROUND AND OBJECTIVES: The goal of methadone maintenance treatment (MMT) is to reduce the harm and to improve patients' quality of life (Qol). However, the Qol is also influenced by other co-occurring disorders. Data regarding the Qol and the co-occurrence of these disorders is lacking in low-middle income countries. We therefore describe the prevalence of physical, psychiatric, and drug abuse co-occurring disorders among MMTpatients in Indonesia and determine the association between the severity of the co-occurring disorders and the Qol. METHODS: Data were collected in 112 injection drug abusers (IDUs) attending a MMT program in West Java, Indonesia, using validated questionnaires, medical records and laboratory testing. For comparison, 154 IDUs not enrolled in MMT were recruited by respondent driven sampling. RESULTS: The most frequent co-occurring disorders were hepatitis C (92%), HIV (77%), benzodiazepine abuse (56%), and anxiety disorders (32%). IDUs in MMT had one (26%), two (47%), or three (27%) co-occurring disorders. Higher severity in psychiatric and physical problems was associated with poorer Qol. IDUs not enrolled in MMT had similar co-occurring problems. CONCLUSIONS: The prevalence of co-occurring disorders in IDUs in Indonesia is high and they influence their Qol. SCIENTIFIC SIGNIFICANCE: Therefore, comprehensive treatment, especially focusing on the common co-occurring disorders should be provided in MMT to improve the Qol.
Authors: Fredrick Dermawan Purba; Joke A M Hunfeld; Aulia Iskandarsyah; Titi Sahidah Fitriana; Sawitri Supardi Sadarjoen; Juan Manuel Ramos-Goñi; Jan Passchier; Jan J V Busschbach Journal: Pharmacoeconomics Date: 2017-11 Impact factor: 4.981
Authors: Mojtaba Salmabadi; Mohammad Faroogh Sadeghbojd; Mohammad Reza Farshad; Shadi Zolfaghari Journal: Int J High Risk Behav Addict Date: 2016-01-30
Authors: Fredrick Dermawan Purba; Joke A M Hunfeld; Aulia Iskandarsyah; Titi Sahidah Fitriana; Sawitri S Sadarjoen; Jan Passchier; Jan J V Busschbach Journal: PLoS One Date: 2018-05-11 Impact factor: 3.240