Identification of molecular recognition of Langmuir-Blodgett monolayers using surface-enhanced Raman scattering spectroscopy.

A facile and effective approach for SERS identification of molecular recognition in Langmuir-Blodgett monolayers on smooth substrates was developed by spreading Ag nanoparticles on ordered alkyl chains in the monolayers, which acted as a spacer layer to separate analytes of interest from direct contact with active substrates.