Literature DB >> 23948853

Site-specific immobilization of biomolecules by a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole.

Ping Wang1, Chong-Jing Zhang, Ganchao Chen, Zhenkun Na, Shao Q Yao, Hongyan Sun.   

Abstract

We report herein a new site-specific microarray immobilization method based on a biocompatible reaction between terminal cysteine and 2-cyanobenzothiazole (CBT). This immobilization strategy has been successfully applied to anchor small molecules, peptides and proteins onto microarrays.

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Year:  2013        PMID： 23948853     DOI： 10.1039/c3cc43566k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Expression of N-Terminal Cysteine Aβ42 and Conjugation to Generate Fluorescent and Biotinylated Aβ42.

Authors:  Sheng Zhang; Gretchen Guaglianone; Michael A Morris; Stan Yoo; William J Howitz; Li Xing; Jian-Guo Zheng; Hannah Jusuf; Grace Huizar; Jonathan Lin; Adam G Kreutzer; James S Nowick
Journal:  Biochemistry       Date:  2021-04-01       Impact factor: 3.321

2.  Iodine-DMSO mediated conversion of N-arylcyanothioformamides to N-arylcyanoformamides and the unexpected formation of 2-cyanobenzothiazoles.

Authors:  Ziad Moussa; Zaher M A Judeh; Ahmed Alzamly; Saleh A Ahmed; Harbi Tomah Al-Masri; Bassam Al-Hindawi; Faisal Rasool; Sara Saada
Journal:  RSC Adv       Date:  2022-02-21       Impact factor: 3.361

3.  Fabrication of a protein microarray by fluorous-fluorous interactions.

Authors:  Ben-Yuan Li; Duane S Juang; Avijit K Adak; Kuo-Chu Hwang; Chun-Cheng Lin
Journal:  Sci Rep       Date:  2017-08-01       Impact factor: 4.379
  3 in total

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