Literature DB >> 23948781

[Surgical treatment of epithelial skin tumors and their precursors].

H-M Häfner1, S Schnabl, H Breuninger, C Schulz.   

Abstract

Squamous cell carcinomas of the skin and their precursors, actinic keratosis as well as basal cell carcinomas are classified as non-melanocytic skin cancer and belong to the group of epithelial skin tumors. This tumor entity is one of the most common forms of malignant cancer in western countries with an incidence of approximately 100-170 per 100,000 inhabitants per year in Europe. In German-speaking countries no exact numbers are available on the early forms of squamous cell carcinoma, actinic keratosis (carcinoma in situ); however, results from Great Britain show that at ages over 70 years old the prevalence of actinic keratosis is 34 % in men and 18 % in women. Because invasive epithelial cancer is very common and most commonly occurs in the head region, a safe but skin-sparing approach to surgical treatment is desirable. The safest procedure with respect to local recurrence is surgical excision with subsequent complete 3-dimensional histological preparation (micrographic surgery). With this method it is possible to excise tissue affected by tumor tissue in small steps. This facilitates defect coverage and leads to very good results as well as good esthetic results. The local recurrence rates are extremely low compared to alternative treatment methods, such as photodynamic therapy, topical application of imiquimod or cryosurgery and for the treatment of basal cell carcinoma, for example is 0.7 %. Dermatological operations are therefore interventions with a very high guarantee of tumor-free survival and functional and esthetic results.

Entities:  

Mesh:

Year:  2013        PMID: 23948781     DOI: 10.1007/s00105-013-2541-1

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  24 in total

1.  Comparison and evaluation of the current staging of cutaneous carcinomas.

Authors:  Helmut Breuninger; Kay Brantsch; Thomas Eigentler; Hans-Martin Häfner
Journal:  J Dtsch Dermatol Ges       Date:  2012-03-07       Impact factor: 5.584

2.  Brief S2k guidelines--Basal cell carcinoma of the skin.

Authors:  Axel Hauschild; Helmut Breuninger; Roland Kaufmann; Rolf-Dieter Kortmann; Martin Klein; Jochen Werner; Julia Reifenberger; Thomas Dirschka; Claus Garbe
Journal:  J Dtsch Dermatol Ges       Date:  2013-06       Impact factor: 5.584

3.  [The chondrocutaneous helical rim advancencement flap--a distinguished method for ear reconstruction].

Authors:  Verena Lichte; Hans-Martin Häfner; Helmut Breuninger; Matthias Möhrle
Journal:  J Dtsch Dermatol Ges       Date:  2009-07       Impact factor: 5.584

4.  Primary wound closure with tension -- tips and tricks.

Authors:  Franziska Carola Eberle; Markus Krug; Helmut Breuninger; Hans-Martin Häfner
Journal:  J Dtsch Dermatol Ges       Date:  2013-04-02       Impact factor: 5.584

5.  3D histology-guided surgery for basal cell carcinoma and squamous cell carcinoma: recurrence rates and clinical outcome.

Authors:  H-M Häfner; H Breuninger; M Moehrle; B Trilling; M Krimmel
Journal:  Int J Oral Maxillofac Surg       Date:  2011-05-19       Impact factor: 2.789

6.  Prevalence of solar damage and actinic keratosis in a Merseyside population.

Authors:  A A Memon; J A Tomenson; J Bothwell; P S Friedmann
Journal:  Br J Dermatol       Date:  2000-06       Impact factor: 9.302

7.  [The margin of safety and depth of excision in surgical treatment of basalioma. Use of 3-dimensional histologic study of 2,016 tumors].

Authors:  H Breuninger; W Schippert; B Black; G Rassner
Journal:  Hautarzt       Date:  1989-11       Impact factor: 0.751

8.  Epidemiology of nonmelanoma skin cancer (NMSC) in Europe: accurate and comparable data are needed for effective public health monitoring and interventions.

Authors:  M Trakatelli; C Ulrich; V del Marmol; S Euvrard; S Euvard; E Stockfleth; D Abeni
Journal:  Br J Dermatol       Date:  2007-05       Impact factor: 9.302

9.  Effect of biopsy type on outcomes in the treatment of primary cutaneous melanoma.

Authors:  Jane K Mills; Ian White; Brian Diggs; Jeanine Fortino; John T Vetto
Journal:  Am J Surg       Date:  2013-05       Impact factor: 2.565

10.  Dysplastic nevus syndrome with development of multiple melanomas. A surgical concept for prophylaxis.

Authors:  Corinna Brod; Wilfried Schippert; Helmut Breuninger
Journal:  J Dtsch Dermatol Ges       Date:  2009-09       Impact factor: 5.584

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  1 in total

1.  Sentinel lymph node biopsy for high-thickness cutaneous squamous cell carcinoma.

Authors:  Lukas Kofler; Katrin Kofler; Claudia Schulz; Helmut Breuninger; Hans-Martin Häfner
Journal:  Arch Dermatol Res       Date:  2020-05-08       Impact factor: 3.017

  1 in total

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