Literature DB >> 23948156

Role of AIF-1 in the regulation of inflammatory activation and diverse disease processes.

Yan-Ying Zhao1, Dong-Jing Yan, Zheng-Wang Chen.   

Abstract

Allograft Inflammatory Factor-1 (AIF-1) is a 17kDa cytoplasmic, calcium-binding, inflammation-responsive scaffold protein that is mainly expressed in immunocytes. AIF-1 influences the immune system at several key points and thus modulates inflammatory diseases. AIF-1 boosts the expression of inflammatory mediators such as cytokines, chemokines, inducible nitric oxide synthase (iNOS) and promotes inflammatory cell proliferation and migration. Here we provide an overview of the different pathological processes regulated by AIF-1 mainly including allograft rejection, autoimmune diseases, central nervous system (CNS) injury, vasculopathy and cancer et al.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AIF-1; Disease processes; Inflammation; Migration; Proliferation

Mesh：

Substances：

Year:  2013        PMID： 23948156     DOI： 10.1016/j.cellimm.2013.07.008

Source DB:  PubMed          Journal:  Cell Immunol        ISSN： 0008-8749            Impact factor:   4.868


  30 in total

1.  Resistance of Biomphalaria glabrata 13-16-R1 snails to Schistosoma mansoni PR1 is a function of haemocyte abundance and constitutive levels of specific transcripts in haemocytes.

Authors:  Maureen K Larson; Randal C Bender; Christopher J Bayne
Journal:  Int J Parasitol       Date:  2014-03-28       Impact factor: 3.981

2.  Loss of Allograft Inflammatory Factor-1 Ameliorates Experimental Autoimmune Encephalomyelitis by Limiting Encephalitogenic CD4 T-Cell Expansion.

Authors:  Prameladevi Chinnasamy; Sarah E Lutz; Dario F Riascos-Bernal; Venkatesh Jeganathan; Isabel Casimiro; Celia F Brosnan; Nicholas E S Sibinga
Journal:  Mol Med       Date:  2015-01-06       Impact factor: 6.354

3.  Some Galeomorph Sharks Express a Mammalian Microglia-Specific Protein in Radial Ependymoglia of the Telencephalon.

Authors:  Skirmantas Janušonis
Journal:  Brain Behav Evol       Date:  2017-12-13       Impact factor: 1.808

4.  Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection.

Authors:  Eamon D Quick; Scott Seitz; Penny Clarke; Kenneth L Tyler
Journal:  J Virol       Date:  2017-10-27       Impact factor: 5.103

5.  R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study.

Authors:  Olena Korvatska; James B Leverenz; Suman Jayadev; Pamela McMillan; Irina Kurtz; Xindi Guo; Malia Rumbaugh; Mark Matsushita; Santhosh Girirajan; Michael O Dorschner; Kostantin Kiianitsa; Chang-En Yu; Zoran Brkanac; Gwenn A Garden; Wendy H Raskind; Thomas D Bird
Journal:  JAMA Neurol       Date:  2015-08       Impact factor: 18.302

6.  Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington's disease.

Authors:  Arlene I Ramsingh; Kevin Manley; Yinghui Rong; Andrew Reilly; Anne Messer
Journal:  Hum Mol Genet       Date:  2015-08-24       Impact factor: 6.150

7.  Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol.

Authors:  Bufang Xu; Mingjuan Zhou; Jingwen Wang; Dan Zhang; Feng Guo; Chenchen Si; Peter C K Leung; Aijun Zhang
Journal:  Hum Reprod       Date:  2018-07-01       Impact factor: 6.918

8.  [Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells].

Authors:  Xiao-Lan Ai; Fang Yao; Xiao-Jing Wang; Dong-Bei Duan; Ke Li; Zi-You Hu; Guo Yin; Mei Wang; Bing-Yi Wu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2018-05-20

9.  Allograft Inflammatory Factor-1 Links T-Cell Activation, Interferon Response, and Macrophage Activation in Chronic Kawasaki Disease Arteritis.

Authors:  Anne H Rowley; Susan C Baker; Kwang-Youn A Kim; Stanford T Shulman; Amy Yang; David Arrollo; Matthew DeBerge; Shuling Han; Nicholas E S Sibinga; Adam J Pink; Edward B Thorp
Journal:  J Pediatric Infect Dis Soc       Date:  2017-09-01       Impact factor: 3.164

10.  Cortical neurons are a prominent source of the proinflammatory cytokine osteopontin in HIV-associated neurocognitive disorders.

Authors:  Katie Silva; Calixto Hope-Lucas; Tyesha White; Tai-Kyung Hairston; Tatenda Rameau; Amanda Brown
Journal:  J Neurovirol       Date:  2015-01-31       Impact factor: 2.643
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.