Literature DB >> 23946259

Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase.

Florian Schlauderer1, Katja Lammens, Daniel Nagel, Michelle Vincendeau, Andrea C Eitelhuber, Steven H L Verhelst, Dale Kling, Al Chrusciel, Jürgen Ruland, Daniel Krappmann, Karl-Peter Hopfner.   

Abstract

Entities:  

Keywords:  cancer; inhibitors; medicinal chemistry; multiple sclerosis; thioridazine

Mesh：

Substances：

Year:  2013        PMID： 23946259     DOI： 10.1002/anie.201304290

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  22 in total

1.  Paracaspase MALT1 regulates glioma cell survival by controlling endo-lysosome homeostasis.

Authors:  Kathryn A Jacobs; Gwennan André-Grégoire; Clément Maghe; An Thys; Ying Li; Elizabeth Harford-Wright; Kilian Trillet; Tiphaine Douanne; Carolina Alves Nicolau; Jean-Sébastien Frénel; Nicolas Bidère; Julie Gavard
Journal:  EMBO J       Date:  2019-11-27       Impact factor: 11.598

Review 2.  The CBM signalosome: potential therapeutic target for aggressive lymphoma?

Authors:  Chenghua Yang; Liron David; Qi Qiao; Ermelinda Damko; Hao Wu
Journal:  Cytokine Growth Factor Rev       Date:  2013-12-24       Impact factor: 7.638

3.  Inhibition of MALT1 Decreases Neuroinflammation and Pathogenicity of Virulent Rabies Virus in Mice.

Authors:  S Van Gucht; R Beyaert; E Kip; J Staal; H G Tima; L Verstrepen; M Romano; K Lemeire; V Suin; A Hamouda; M Baens; C Libert; M Kalai
Journal:  J Virol       Date:  2018-10-29       Impact factor: 5.103

4.  Probes to monitor activity of the paracaspase MALT1.

Authors:  Janna Hachmann; Laura E Edgington-Mitchell; Marcin Poreba; Laura E Sanman; Marcin Drag; Matthew Bogyo; Guy S Salvesen
Journal:  Chem Biol       Date:  2014-12-31

5.  Pharmacological inhibition of MALT1 protease activity suppresses endothelial activation via enhancing MCPIP1 expression.

Authors:  Yong Li; Shengping Huang; Xuan Huang; Xiuzhen Li; Adrian Falcon; Adele Soutar; Frederic Bornancin; Zhisheng Jiang; Hong-Bo Xin; Mingui Fu
Journal:  Cell Signal       Date:  2018-06-18       Impact factor: 4.315

6.  Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.

Authors:  Pieter Van Vlierberghe; Steven Goossens; Tim Pieters; Sara T'Sas; Stijn Vanhee; André Almeida; Yasmine Driege; Juliette Roels; Wouter Van Loocke; Willem Daneels; Mathijs Baens; Arnaud Marchand; Maaike Van Trimpont; Filip Matthijssens; Julie Morscio; Kelly Lemeire; Béatrice Lintermans; Lindy Reunes; Patrick Chaltin; Fritz Offner; Jo Van Dorpe; Tino Hochepied; Geert Berx; Rudi Beyaert; Jens Staal
Journal:  J Exp Med       Date:  2021-08-18       Impact factor: 14.307

Review 7.  The Paracaspase MALT1.

Authors:  Janna Hachmann; Guy S Salvesen
Journal:  Biochimie       Date:  2015-09-16       Impact factor: 4.079

8.  Thioridazine requires calcium influx to induce MLL-AF6-rearranged AML cell death.

Authors:  Claudia Tregnago; Ambra Da Ros; Elena Porcù; Maddalena Benetton; Manuela Simonato; Luca Simula; Giulia Borella; Katia Polato; Sonia Minuzzo; Giulia Borile; Paola Cogo; Silvia Campello; Alessandro Massi; Romeo Romagnoli; Barbara Buldini; Franco Locatelli; Martina Pigazzi
Journal:  Blood Adv       Date:  2020-09-22

9.  Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase.

Authors:  Catarina Coelho; Alessandro Foti; Tobias Hartmann; Teresa Santos-Silva; Silke Leimkühler; Maria João Romão
Journal:  Nat Chem Biol       Date:  2015-08-31       Impact factor: 15.040

10.  MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage.

Authors:  Linda R Klei; Dong Hu; Robert Panek; Danielle N Alfano; Rachel E Bridwell; Kelly M Bailey; Katherine I Oravecz-Wilson; Vincent J Concel; Emily M Hess; Matthew Van Beek; Phillip C Delekta; Shufang Gu; Simon C Watkins; Adrian T Ting; Peter J Gough; Kevin P Foley; John Bertin; Linda M McAllister-Lucas; Peter C Lucas
Journal:  Cell Rep       Date:  2016-09-27       Impact factor: 9.423
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