| Literature DB >> 23946251 |
Yuting Niu1, Meihua Yu, Sandy B Hartono, Jie Yang, Hongyi Xu, Hongwei Zhang, Jun Zhang, Jin Zou, Annette Dexter, Wenyi Gu, Chengzhong Yu.
Abstract
Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20 μm).Entities:
Keywords: biomimetic synthesis; drug delivery; nanoparticles; surface topography
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Year: 2013 PMID: 23946251 DOI: 10.1002/adma.201302737
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849