Literature DB >> 23945064

A qualitative study of experiences with and perceptions regarding long-acting injectable antipsychotics: part II-physician perspectives.

Srividya Iyer1, Nicola Banks, Marc-André Roy, Phil Tibbo, Richard Williams, Rahul Manchanda, Pierre Chue, Ashok Malla.   

Abstract

OBJECTIVE: In many countries, including Canada, a small proportion of people with psychotic disorders receive long-acting injectable (LAI) antipsychotics (APs), despite their demonstrated effectiveness and possible advantages for improving adherence rates. Attitudes regarding LAIs among physicians may influence their prescribing practices and thereby contribute to the underuse of LAIs. Here, we report on a qualitative study of perceptions and attitudes toward LAIs among psychiatrists in Canada.
METHOD: Focus groups were conducted with 24 psychiatrists in 4 Canadian provinces. The focus groups inquired about experiences with and attitudes toward LAI APs. The sessions were audiotaped and transcribed verbatim, and transcripts were coded using a hybrid process of deductive and inductive methods. A brief pre-focus group questionnaire was administered.
RESULTS: The pre-focus group questionnaires indicated that psychiatrists in our study prescribed the oral formulation of APs most of the time and had limited experience with LAIs. The focus groups yielded 4 main themes: limited knowledge about and experience with LAIs; attitudes toward LAIs (beliefs about negative perceptions of patients regarding LAIs, personal bias against needles, and consensus about some advantages of LAIs); prescribing practices around LAIs (generally seen as a last-resort option for patients with a history of nonadherence); and pragmatic barriers to using LAIs (for example, cost, storage, and staffing).
CONCLUSION: Several factors may be contributing to the underuse of LAIs and the continuing stigmatized and coercive image of LAIs. Psychiatrists may benefit from better education about LAIs, and from self-examination of their attitudes to LAIs and their prescribing practices.

Entities:  

Keywords:  antipsychotic long-acting injections; depot antipsychotics; first-generation antipsychotics; focus group; physician attitudes; second-generation antipsychotics

Mesh:

Substances:

Year:  2013        PMID: 23945064     DOI: 10.1177/088740341305805s04

Source DB:  PubMed          Journal:  Can J Psychiatry        ISSN: 0706-7437            Impact factor:   4.356


  12 in total

1.  Patients' Preference for Long-Acting Injectable versus Oral Antipsychotics in Schizophrenia: Results from the Patient-Reported Medication Preference Questionnaire.

Authors:  Clifton Blackwood; Panna Sanga; Isaac Nuamah; Alexander Keenan; Arun Singh; Maju Mathews; Srihari Gopal
Journal:  Patient Prefer Adherence       Date:  2020-07-02       Impact factor: 2.711

Review 2.  [Advantages and controversies of depot antipsychotics in the treatment of patients with schizophrenia].

Authors:  S Breit; G Hasler
Journal:  Nervenarzt       Date:  2016-07       Impact factor: 1.214

3.  Modeling determinants of medication attitudes and poor adherence in early nonaffective psychosis: implications for intervention.

Authors:  Richard J Drake; Merete Nordentoft; Gillian Haddock; Celso Arango; W Wolfgang Fleischhacker; Birte Glenthøj; Marion Leboyer; Stefan Leucht; Markus Leweke; Phillip McGuire; Andreas Meyer-Lindenberg; Dan Rujescu; Iris E Sommer; René S Kahn; Shon W Lewis
Journal:  Schizophr Bull       Date:  2015-03-05       Impact factor: 9.306

Review 4.  Barriers to the Use of Long-Acting Injectable Antipsychotics in the Management of Schizophrenia.

Authors:  Eduard Parellada; Miquel Bioque
Journal:  CNS Drugs       Date:  2016-08       Impact factor: 5.749

Review 5.  What Is the Place of Clozapine in the Treatment of Early Psychosis in Canada?

Authors:  Richard Williams; Ashok Malla; Marc-Andre Roy; Ridha Joober; Rahul Manchanda; Phil Tibbo; Nicola Banks; Ofer Agid
Journal:  Can J Psychiatry       Date:  2016-07-09       Impact factor: 4.356

6.  Clinical Decision-Making in the Treatment of Schizophrenia: Focus on Long-Acting Injectable Antipsychotics.

Authors:  Ludovic Samalin; Marion Garnier; Candy Auclair; Pierre-Michel Llorca
Journal:  Int J Mol Sci       Date:  2016-11-19       Impact factor: 5.923

7.  Real-life assessment of aripiprazole monthly (Abilify Maintena) in schizophrenia: a Canadian naturalistic non-interventional prospective cohort study.

Authors:  Sally Mustafa; Joanna Bougie; Maia Miguelez; Guerline Clerzius; Emmanouil Rampakakis; Jean Proulx; Ashok Malla
Journal:  BMC Psychiatry       Date:  2019-04-16       Impact factor: 3.630

Review 8.  Pharmacokinetic Characteristics of Long-Acting Injectable Antipsychotics for Schizophrenia: An Overview.

Authors:  Christoph U Correll; Edward Kim; Jennifer Kern Sliwa; Wayne Hamm; Srihari Gopal; Maju Mathews; Raja Venkatasubramanian; Stephen R Saklad
Journal:  CNS Drugs       Date:  2021-01-28       Impact factor: 5.749

9.  Reasons for initiating long-acting antipsychotics in psychiatric practice: findings from the STAR Network Depot Study.

Authors:  Corrado Barbui; Federico Bertolini; Francesco Bartoli; Carmela Calandra; Camilla Callegari; Giuseppe Carrà; Armando D'Agostino; Claudio Lucii; Giovanni Martinotti; Daniele Mastromo; Daniele Moretti; Emiliano Monzani; Matteo Porcellana; Davide Prestia; Giovanni Ostuzzi
Journal:  Ther Adv Psychopharmacol       Date:  2020-12-22

10.  A qualitative study of physician perspectives of cost-related communication and patients' financial burden with managing chronic disease.

Authors:  Minal R Patel; Khooshbu S Shah; Meagan L Shallcross
Journal:  BMC Health Serv Res       Date:  2015-11-25       Impact factor: 2.655

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