Literature DB >> 23943540

Fabrication of red-blood-cell-like polyelectrolyte microcapsules and their deformation and recovery behavior through a microcapillary.

Shupeng She1, Qinqin Li, Bowen Shan, Weijun Tong, Changyou Gao.   

Abstract

Multilayer microcapsules with a biconcave discoidal shape mimicking red blood cells (RBCs) are fabricated. The structure of the RBC-like microcapsules is verified by scanning electron and confocal laser scanning microscopies. The capsules show elastic deformation after being forced through a microcapillary with a smaller diameter, exhibiting a high recovery ratio of ≈90%. When the capsules are coated with hemoglobin (Hb),they are able to reversibly bind and release oxygen.
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biomedical applications; biomimetics; layer-by-layer (LbL); microcapsules; oxygen delivery; red blood cells

Mesh：

Substances：

Year:  2013        PMID： 23943540     DOI： 10.1002/adma.201302875

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  8 in total

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Journal:  ACS Appl Mater Interfaces       Date:  2019-01-28       Impact factor: 9.229

Review 2.  Non-affinity factors modulating vascular targeting of nano- and microcarriers.

Authors:  Jacob W Myerson; Aaron C Anselmo; Yaling Liu; Samir Mitragotri; David M Eckmann; Vladimir R Muzykantov
Journal:  Adv Drug Deliv Rev       Date:  2015-10-24       Impact factor: 15.470

Review 3.  Spatio-Temporal Control of LbL Films for Biomedical Applications: From 2D to 3D.

Authors:  Claire Monge; Jorge Almodóvar; Thomas Boudou; Catherine Picart
Journal:  Adv Healthc Mater       Date:  2015-01-27       Impact factor: 9.933

4.  Internalization of red blood cell-mimicking hydrogel capsules with pH-triggered shape responses.

Authors:  Veronika Kozlovskaya; Jenolyn F Alexander; Yun Wang; Thomas Kuncewicz; Xuewu Liu; Biana Godin; Eugenia Kharlampieva
Journal:  ACS Nano       Date:  2014-05-27       Impact factor: 15.881

5.  Design of a Novel Oxygen Therapeutic Using Polymeric Hydrogel Microcapsules Mimicking Red Blood Cells.

Authors:  Amanda Cherwin; Shelby Namen; Justyna Rapacz; Grace Kusik; Alexa Anderson; Yale Wang; Matey Kaltchev; Rebecca Schroeder; Kellen O'Connell; Sydney Stephens; Junhong Chen; Wujie Zhang
Journal:  Pharmaceutics       Date:  2019-11-07       Impact factor: 6.321

Review 6.  Properties and Applications of PDMS for Biomedical Engineering: A Review.

Authors:  Inês Miranda; Andrews Souza; Paulo Sousa; João Ribeiro; Elisabete M S Castanheira; Rui Lima; Graça Minas
Journal:  J Funct Biomater       Date:  2021-12-21

Review 7.  Blood Particulate Analogue Fluids: A Review.

Authors:  Samir Hassan Sadek; Manuel Rubio; Rui Lima; Emilio José Vega
Journal:  Materials (Basel)       Date:  2021-05-09       Impact factor: 3.623

Review 8.  Microfluidic Synthesis and Analysis of Bioinspired Structures Based on CaCO3 for Potential Applications as Drug Delivery Carriers.

Authors:  Ekaterina V Lengert; Daria B Trushina; Mikhail Soldatov; Alexey V Ermakov
Journal:  Pharmaceutics       Date:  2022-01-07       Impact factor: 6.321
  8 in total

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