Literature DB >> 2394318

Mosquito oostatic factor: a novel decapeptide modulating trypsin-like enzyme biosynthesis in the midgut.

D Borovsky1, D A Carlson, P R Griffin, J Shabanowitz, D F Hunt.   

Abstract

A peptide that inhibits egg development in mosquitoes (oostatic factor) has been purified from the ovaries of female Aedes aegypti. The factor is a decapeptide with a molecular mass of 1047.6. The primary sequence has been determined as NH2-Tyr-Asp-Pro-Ala-Pro-Pro-Pro-Pro-Pro-Pro-COOH from mass spectra recorded on a quadrupole Fourier transform instrument. The amino acid sequence exhibits sequence correlation to mammalian, plant, and several viral proteins. Injection of synthetic analogs into mosquitoes, biting midges, flies, and fleas inhibited proteolytic enzyme biosynthesis in the midgut. Binding studies with [3H]oostatic factor indicated that the midgut epithelial cells have a factor-specific receptor.

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Year:  1990        PMID： 2394318     DOI： 10.1096/fasebj.4.12.2394318

Source DB:  PubMed          Journal:  FASEB J        ISSN： 0892-6638            Impact factor:   5.191


  15 in total

1.  A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family.

Authors:  K Niebuhr; F Ebel; R Frank; M Reinhard; E Domann; U D Carl; U Walter; F B Gertler; J Wehland; T Chakraborty
Journal:  EMBO J       Date:  1997-09-01       Impact factor: 11.598

2.  BT-engineered bugs versus insect pests.

Authors:  Alejandro G Pardo
Journal:  Bioeng Bugs       Date:  2010 Sep-Oct

3.  Trypsin-modulating oostatic factor (TMOF) decreased the survival, growth and digestion enzymes of Macrobrachium rosenbergii.

Authors:  Akeem Babatunde Dauda; Jun Chin Teh; S M Nurul Amin; Mohd Salleh Kamarudin; Nicholas Romano
Journal:  J Pestic Sci       Date:  2016-08-20       Impact factor: 1.519

4.  Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV: A potential larvicide.

Authors:  Dov Borovsky; Shailaja Rabindran; William O Dawson; Charles A Powell; Donna A Iannotti; Timothy J Morris; Jeffry Shabanowitz; Donald F Hunt; Hendrik L DeBondt; Arnold DeLoof
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-05       Impact factor: 11.205

Review 5.  The Role of Peptide Hormones in Insect Lipid Metabolism.

Authors:  Umut Toprak
Journal:  Front Physiol       Date:  2020-05-07       Impact factor: 4.566

6.  Transgenic organisms expressing genes from Bacillus thuringiensis to combat insect pests.

Authors:  Arieh Zaritsky; Eitan Ben-Dov; Dov Borovsky; Sammy Boussiba; Monica Einav; Galina Gindin; A Rami Horowitz; Mikhail Kolot; Olga Melnikov; Zvi Mendel; Ezra Yagil
Journal:  Bioeng Bugs       Date:  2010 Sep-Oct

7.  An insect peptide engineered into the tomato prosystemin gene is released in transgenic tobacco plants and exerts biological activity.

Authors:  Claudia Tortiglione; Vincenzo Fogliano; Rosalia Ferracane; Paolo Fanti; Francesco Pennacchio; Luigi Maria Monti; Rosa Rao
Journal:  Plant Mol Biol       Date:  2003-12       Impact factor: 4.076

8.  Inhibition of Listeria locomotion by mosquito oostatic factor, a natural oligoproline peptide uncoupler of profilin action.

Authors:  F S Southwick; D L Purich
Journal:  Infect Immun       Date:  1995-01       Impact factor: 3.441

9.  Study of oostatic peptide uptake and metabolism in developing ovaries of the flesh fly, Neobellieria bullata.

Authors:  Blanka Bennettová; Jirina Slaninová; Vĕra Vlasáková; Jan Hlavácek; Josef Holík; Richard Tykva
Journal:  J Insect Sci       Date:  2010       Impact factor: 1.857

10.  The Ribosome Is the Ultimate Receptor for Trypsin Modulating Oostatic Factor (TMOF).

Authors:  Dov Borovsky; Pierre Rougé; Robert G Shatters
Journal:  Biomolecules       Date:  2022-04-14
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