| Literature DB >> 23942057 |
Mohammad A Rai1, Yonghong Zhang, Louis-M Yindom, Jane Holmes, Ly-Mee Yu, Chun Hao, Tim Rostron, Huiping Yan, Yong Li Zhang, Chao Cai, Andrew J McMichael, Tao Dong, Sarah L Rowland-Jones, Marie-E Blais, Ke Yi Xu.
Abstract
We looked at our HIV + slow progressors cohort to determine if there were any human leukocyte antigen (HLA) correlates for protection. No statistically significant allelic differences were found between the HIV + and control cohorts using regression analysis, though trends were noted. Data for Elite Controllers showed an increased frequency of B*57. Likewise, no correlation was inferred with the clinical data of the HIV + cohort. We hypothesize that the protective effect of HLA alleles may have been lost over time.Entities:
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Year: 2013 PMID： 23942057 DOI： 10.1097/QAD.0000000000000011
Source DB: PubMed Journal: AIDS ISSN： 0269-9370 Impact factor: 4.177