Literature DB >> 23939933

Vinylsulfonamide and acrylamide modification of DNA for cross-linking with proteins.

Jitka Dadová1, Petr Orság, Radek Pohl, Marie Brázdová, Miroslav Fojta, Michal Hocek.   

Abstract

Bioorthogonal covalent cross-linking of DNA-binding proteins (p53) to DNA was achieved through novel DNA probes bearing a reactive vinylsulfonamide (VS) group. The VS-modified dCTP served as building block for polymerase synthesis of modified DNA, which was readily conjugated with cysteine-containing peptides and proteins by Michael addition.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  DNA; DNA polymerase; Michael additions; bioorthogonal chemistry; proteins

Mesh：

Substances：

Year:  2013        PMID： 23939933     DOI： 10.1002/anie.201303577

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  17 in total

Review 1.  The Toolbox for Modified Aptamers.

Authors:  Sergey A Lapa; Alexander V Chudinov; Edward N Timofeev
Journal:  Mol Biotechnol       Date:  2016-02       Impact factor: 2.695

2.  A Platform for Site-Specific DNA-Antibody Bioconjugation by Using Benzoylacrylic-Labelled Oligonucleotides.

Authors:  Juraj Konč; Libby Brown; Daniel R Whiten; Yukun Zuo; Peter Ravn; David Klenerman; Gonçalo J L Bernardes
Journal:  Angew Chem Int Ed Engl       Date:  2021-11-03       Impact factor: 16.823

3.  On-Resin Macrocyclization of Peptides Using Vinyl Sulfonamides as a Thiol-Michael "Click" Acceptor.

Authors:  Bryan P Sutherland; Bassil M El-Zaatari; Nicole I Halaszynski; Jonathan M French; Shi Bai; Christopher J Kloxin
Journal:  Bioconjug Chem       Date:  2018-11-26       Impact factor: 4.774

4.  Vinyluridine as a Versatile Chemoselective Handle for the Post-transcriptional Chemical Functionalization of RNA.

Authors:  Jerrin Thomas George; Seergazhi G Srivatsan
Journal:  Bioconjug Chem       Date:  2017-04-26       Impact factor: 4.774

Review 5.  Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics.

Authors:  Emil Paleček; Jan Tkáč; Martin Bartošík; Tomáš Bertók; Veronika Ostatná; Jan Paleček
Journal:  Chem Rev       Date:  2015-02-09       Impact factor: 60.622

6.  Protein Labeling and Crosslinking by Covalent Aptamers.

Authors:  Yaniv Tivon; Gianna Falcone; Alexander Deiters
Journal:  Angew Chem Int Ed Engl       Date:  2021-06-09       Impact factor: 16.823

7.  Probing interactions between lysine residues in histone tails and nucleosomal DNA via product and kinetic analysis.

Authors:  Liwei Weng; Chuanzheng Zhou; Marc M Greenberg
Journal:  ACS Chem Biol       Date:  2014-12-05       Impact factor: 5.100

8.  Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation.

Authors:  Kuan-Chuan Pao; Mathew Stanley; Cong Han; Yu-Chiang Lai; Paul Murphy; Kristin Balk; Nicola T Wood; Olga Corti; Jean-Christophe Corvol; Miratul M K Muqit; Satpal Virdee
Journal:  Nat Chem Biol       Date:  2016-03-07       Impact factor: 15.040

9.  Pyrimidine Nucleosides with a Reactive (β-Chlorovinyl)sulfone or (β-Keto)sulfone Group at the C5 Position, Their Reactions with Nucleophiles and Electrophiles, and Their Polymerase-Catalyzed Incorporation into DNA.

Authors:  Sazzad H Suzol; A Hasan Howlader; Zhiwei Wen; Yaou Ren; Eduardo E Laverde; Carol Garcia; Yuan Liu; Stanislaw F Wnuk
Journal:  ACS Omega       Date:  2018-04-16

10.  Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions.

Authors:  Jana Balintová; Jan Špaček; Radek Pohl; Marie Brázdová; Luděk Havran; Miroslav Fojta; Michal Hocek
Journal:  Chem Sci       Date:  2014-09-16       Impact factor: 9.825
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