Daniel G Fuller1, Katlyn Potts, Jeung Kim. 1. *OD, FAAO †BS ‡OD, PhD The Eye Center, Southern College of Optometry, Memphis, Tennessee (DGF, JK); and Southern College of Optometry, Memphis, Tennessee (KP).
Abstract
PURPOSE: To investigate the correlation between the Ocular Surface Disease Index (OSDI) Questionnaire and noninvasive tear breakup times (NITBUTs) obtained by the Keratograph 4 (Oculus, Wetzlar, Germany) device. METHODS: A prospective sequential study of subjects (N = 99) unmatched for sex and without a significant difference in age by sex was performed. Testing included administration of OSDI, followed by Keratograph 4 measurements of the first NITBUT (NITBUT(f)) and average NITBUT (NITBUT(av)). RESULTS: The NITBUT(f) was significantly shorter than NITBUT(av), as tested by Mann-Whitney statistic (U = 7331.5, <0.0001). The NITBUT(f) and NITBUT(av) demonstrated identical statistically significant Spearman correlations with OSDI (r(s) = -0.20, p = 0.05). CONCLUSIONS: Ocular Surface Disease Index and NITBUT testing by Keratograph 4 device demonstrate a weak, but statistically significant, negative correlation.
PURPOSE: To investigate the correlation between the Ocular Surface Disease Index (OSDI) Questionnaire and noninvasive tear breakup times (NITBUTs) obtained by the Keratograph 4 (Oculus, Wetzlar, Germany) device. METHODS: A prospective sequential study of subjects (N = 99) unmatched for sex and without a significant difference in age by sex was performed. Testing included administration of OSDI, followed by Keratograph 4 measurements of the first NITBUT (NITBUT(f)) and average NITBUT (NITBUT(av)). RESULTS: The NITBUT(f) was significantly shorter than NITBUT(av), as tested by Mann-Whitney statistic (U = 7331.5, <0.0001). The NITBUT(f) and NITBUT(av) demonstrated identical statistically significant Spearman correlations with OSDI (r(s) = -0.20, p = 0.05). CONCLUSIONS: Ocular Surface Disease Index and NITBUT testing by Keratograph 4 device demonstrate a weak, but statistically significant, negative correlation.
Authors: Mana A Alanazi; Gamal A El-Hiti; Rashid Al-Tamimi; Abdullah M Bawazir; Essam S Almutleb; Raied Fagehi; Saud A Alanazi; Ali M Masmali Journal: J Ophthalmol Date: 2022-08-16 Impact factor: 1.974