| Literature DB >> 23939121 |
Yong Zhou1, Junjie Yao, Lihong V Wang.
Abstract
Due to strong light scattering in tissue, both the spatial resolution and maximum penetration depth of optical-resolution photoacoustic microscopy (OR-PAM) deteriorate sharply with depth. To reduce tissue scattering, we propose to use glycerol as an optical clearing agent in OR-PAM. Our results show that the imaging performance of OR-PAM can be greatly enhanced by optical clearing both in vitro and in vivo.Entities:
Mesh:
Year: 2013 PMID: 23939121 PMCID: PMC3759812 DOI: 10.1364/OL.38.002592
Source DB: PubMed Journal: Opt Lett ISSN: 0146-9592 Impact factor: 3.776