Literature DB >> 23939011

Experimental verification of dose calculation using the simplified Monte Carlo method with an improved initial beam model for a beam-wobbling system.

Ryohei Tansho1, Yoshihisa Takada, Ryosuke Kohno, Kenji Hotta, Yousuke Hara, Shohei Mizutani, Tetsuo Akimoto.   

Abstract

A beam delivery system using a single-radius-beam-wobbling method has been used to form a conformal irradiation field for proton radiotherapy in Japan. A proton beam broadened by the beam-wobbling system provides a non-Gaussian distribution of projection angle different in two mutually orthogonal planes with a common beam central axis, at a certain position. However, the conventional initial beam model for dose calculations has been using an approximation of symmetric Gaussian angular distribution with the same variance in both planes (called here a Gaussian model with symmetric variance (GMSV)), instead of the accurate one. We have developed a more accurate initial beam model defined as a non-Gaussian model with asymmetric variance (NonGMAV), and applied it to dose calculations using the simplified Monte Carlo (SMC) method. The initial beam model takes into account the different distances of two beam-wobbling magnets from the iso-center and also the different amplitudes of kick angle given by each magnet. We have confirmed that the calculation using the SMC with NonGMAV reproduced the measured dose distribution formed in air by a mono-energetic proton beam passing through a square aperture collimator better than with the GMSV and with a Gaussian model with asymmetric variance (GMAV) in which different variances of angular distributions are used in the two mutually orthogonal planes. Measured dose distributions in a homogeneous phantom formed by a modulated proton beam passing through a range shifter and an L-shaped range compensator, were consistent with calculations using the SMC with GMAV and NonGMAV, but in disagreement with calculations using the SMC with GMSV. Measured lateral penumbrae in a lateral direction were reproduced better by calculations using the SMC with NonGMAV than by those with GMAV, when an aperture collimator with a smaller opening was used. We found that such a difference can be attributed to the non-Gaussian angular distribution of the initial beam at a lateral position for the beam-wobbling system. Calculations using the SMC with NonGMAV are effective to reproduce dose distributions formed by a beam-wobbling system more accurately than that with GMSV or that with GMAV.

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Year:  2013        PMID: 23939011     DOI: 10.1088/0031-9155/58/17/6047

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  2 in total

1.  Impact of lifetime attributable risk of radiation-induced secondary cancer in proton craniospinal irradiation with vertebral-body-sparing for young pediatric patients with medulloblastoma.

Authors:  Shunsuke Suzuki; Takahiro Kato; Masao Murakami
Journal:  J Radiat Res       Date:  2021-03-10       Impact factor: 2.724

2.  A validated proton beam therapy patch-field protocol for effective treatment of large hepatocellular carcinoma.

Authors:  Masatoshi Nakamura; Nobuyoshi Fukumitsu; Satoshi Kamizawa; Haruko Numajiri; Keiko Nemoto Murofushi; Kayoko Ohnishi; Teruhito Aihara; Hitoshi Ishikawa; Toshiyuki Okumura; Koji Tsuboi; Hideyuki Sakurai
Journal:  J Radiat Res       Date:  2018-09-01       Impact factor: 2.724

  2 in total

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