Literature DB >> 23934700

Identification of malate dehydrogenase 2 as a target protein of the HIF-1 inhibitor LW6 using chemical probes.

Kyeong Lee1, Hyun Seung Ban, Ravi Naik, Ye Seul Hong, Seohyun Son, Bo-Kyung Kim, Yan Xia, Kyung Bin Song, Hong-Sub Lee, Misun Won.   

Abstract

Entities:  

Keywords:  HIF inhibitors; click chemistry; fluorescent probes; malate dehydrogenase 2; photoaffinity labeling

Mesh：

Substances：

Year:  2013        PMID： 23934700     DOI： 10.1002/anie.201304987

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  22 in total

1.  Comparison of the effect of the aerobic glycolysis inhibitor dichloroacetate and of the Krebs cycle inhibitor LW6 on cellular and humoral alloimmunity.

Authors:  Theodoros Eleftheriadis; Georgios Pissas; Athanasios Mavropoulos; Vassilios Liakopoulos; Ioannis Stefanidis
Journal:  Biomed Rep       Date:  2017-09-11

Review 2.  Developments of bioorthogonal handle-containing photo-crosslinkers for photoaffinity labeling.

Authors:  Haijun Guo; Zhengqiu Li
Journal:  Medchemcomm       Date:  2017-06-14       Impact factor: 3.597

3.  Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids.

Authors:  Bit Lee; Wei Sun; Hyungjun Lee; Halesha Basavarajappa; Rania S Sulaiman; Kamakshi Sishtla; Xiang Fei; Timothy W Corson; Seung-Yong Seo
Journal:  Bioorg Med Chem Lett       Date:  2016-07-21       Impact factor: 2.823

4.  Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.

Authors:  André Mateus; Laurie J Gordon; Gareth J Wayne; Helena Almqvist; Hanna Axelsson; Brinton Seashore-Ludlow; Andrea Treyer; Pär Matsson; Thomas Lundbäck; Andy West; Michael M Hann; Per Artursson
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-12       Impact factor: 11.205

5.  Mincle Signaling Promotes Con A Hepatitis.

Authors:  Stephanie H Greco; Alejandro Torres-Hernandez; Aleksandr Kalabin; Clint Whiteman; Rae Rokosh; Sushma Ravirala; Atsuo Ochi; Johana Gutierrez; Muhammad Atif Salyana; Vishnu R Mani; Savitha V Nagaraj; Michael Deutsch; Lena Seifert; Donnele Daley; Rocky Barilla; Mautin Hundeyin; Yuriy Nikifrov; Karla Tejada; Bruce E Gelb; Steven C Katz; George Miller
Journal:  J Immunol       Date:  2016-08-24       Impact factor: 5.422

Review 6.  Photoaffinity labelling strategies for mapping the small molecule-protein interactome.

Authors:  Nikolas R Burton; Phillip Kim; Keriann M Backus
Journal:  Org Biomol Chem       Date:  2021-09-22       Impact factor: 3.890

Review 7.  The role of hypoxia-inducible factors in metabolic diseases.

Authors:  Frank J Gonzalez; Cen Xie; Changtao Jiang
Journal:  Nat Rev Endocrinol       Date:  2018-12       Impact factor: 43.330

8.  Malate dehydrogenase-2 inhibitor LW6 promotes metabolic adaptations and reduces proliferation and apoptosis in activated human T-cells.

Authors:  Theodoros Eleftheriadis; Georgios Pissas; Georgia Antoniadi; Vassilios Liakopoulos; Ioannis Stefanidis
Journal:  Exp Ther Med       Date:  2015-09-22       Impact factor: 2.447

9.  Organization of enzyme concentration across the metabolic network in cancer cells.

Authors:  Neel S Madhukar; Marc O Warmoes; Jason W Locasale
Journal:  PLoS One       Date:  2015-01-26       Impact factor: 3.240

Review 10.  Photoaffinity labeling in target- and binding-site identification.

Authors:  Ewan Smith; Ian Collins
Journal:  Future Med Chem       Date:  2015       Impact factor: 3.808
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