Literature DB >> 23933969

Metabolic phenotyping of diabetic nephropathy.

V-P Mäkinen1, A J Kangas, P Soininen, P Würtz, P-H Groop, M Ala-Korpela.   

Abstract

Diabetic nephropathy is the most serious complication of type 1 diabetes. There is no treatment to protect the kidneys from poorly controlled diabetes, and therefore prevention of the initial metabolic insults is currently the only effective approach to reducing the high mortality related to diabetic nephropathy. Metabolic phenotyping brings us one step closer to understanding the unique set of regulatory perturbations that predispose to kidney injury and paves the way for multiparametric risk assessment.

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Year:  2013        PMID: 23933969     DOI: 10.1038/clpt.2013.158

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


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