Literature DB >> 23932600

Tuberculin skin test conversion rate among short-term health care workers returning from Gaborone, Botswana.

Zsofia Szep1, Rose Kim2, Sarah J Ratcliffe3, Stephen Gluckman4.   

Abstract

UNLABELLED: Our objective was to determine tuberculin skin test conversion rate of health care workers traveling to Botswana. The rate of tuberculin skin test conversion was 4.2% for the entire group studied or 6.87 per 1000 person weeks (95% CI, 1.87-17.60).
BACKGROUND: International travel by health care workers traveling from low incidence countries to areas of the world where tuberculosis is highly endemic places the health care worker at an increased risk of acquiring tuberculosis.
OBJECTIVES: To determine the tuberculin skin test conversion rate of health care workers living in the United States with previously negative tuberculin skin test results working for less than 1 year in a hospital in Botswana where tuberculosis is highly endemic.
METHODS: We performed a cross-sectional survey among health care workers affiliated with the University of Pennsylvania School of Medicine who participated in patient care in Botswana between July 1st 2004 and June 30th 2009. We recruited health care workers after returning from Botswana who had a documented negative tuberculin skin test in the year prior to travel, who spent at least 2 weeks but not more than 1 year and who had a documented tuberculin skin test 2-3 months post travel. The main study outcome was a positive tuberculin skin test 6-12 weeks after returning from Botswana, defined by an area of at least 10mm induration 48-72h after placement of the tuberculin skin test.
RESULTS: 95 Subjects participated in the study and there were 4 tuberculin skin test conversions. The rate of tuberculin skin test conversion in our study population was 4.2% for the entire group studied or 6.87 per 1000 person weeks (95% CI, 1.87-17.60).
CONCLUSIONS: The tuberculin skin test conversion rate was higher than the reported conversion rates for those not working in a health care setting.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Mycobacterium tuberculosis; Tuberculin skin test; Tuberculosis diagnosis

Mesh:

Year:  2013        PMID: 23932600     DOI: 10.1016/j.tmaid.2013.07.002

Source DB:  PubMed          Journal:  Travel Med Infect Dis        ISSN: 1477-8939            Impact factor:   6.211


  3 in total

1.  Risk of latent and active tuberculosis infection in travellers: a systematic review and meta-analysis.

Authors:  Tanya R Diefenbach-Elstob; Balqis Alabdulkarim; Paromita Deb-Rinker; Jeffrey M Pernica; Guido Schwarzer; Dick Menzies; Ian Shrier; Kevin Schwartzman; Christina Greenaway
Journal:  J Travel Med       Date:  2021-01-06       Impact factor: 8.490

2.  Indicators to assess the quality of programs to prevent occupational risk for tuberculosis: are they feasible?

Authors:  Talita Raquel Dos Santos; Maria Clara Padoveze; Lúcia Yasuko Izumi Nichiata; Renata Ferreira Takahashi; Suely Itsuko Ciosak; Anna Luiza de Fátima Pinho Lins Gryschek
Journal:  Rev Lat Am Enfermagem       Date:  2016-06-07

3.  Relationship between expression mRNA gene Treg, Treg, CD4+, and CD8+ protein levels with TST in tuberculosis children: A nested case-control.

Authors:  Rahmini Shabariah; Mochammad Hatta; Ilhamjaya Patellongi; Muh Nasrum Massi; Andi Asadul Islam; Rosdiana Natzir; Andi Dwi Bahagia Febriani; Firdaus Hamid; Risky Akaputra; Pitut Aprilia Savitri
Journal:  Ann Med Surg (Lond)       Date:  2020-12-19
  3 in total

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