Literature DB >> 23931139

TGF-β antagonists: same knot, but different hold.

Andrew P Hinck1, Tao Huang.   

Abstract

In this issue of Structure, Nolan and colleagues present the structure of BMP antagonist, PRDC, which adopts a head-to-tail dimer with distinct structure and inhibitory mechanism compared to other dimeric antagonists of the TGF-β superfamily, such as noggin.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID： 23931139      PMCID： PMC3809007          DOI： 10.1016/j.str.2013.07.015

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  8 in total

Review 1.  Transcriptional control by the TGF-beta/Smad signaling system.

Authors:  J Massagué; D Wotton
Journal:  EMBO J       Date:  2000-04-17       Impact factor: 11.598

2.  Structural basis of BMP signalling inhibition by the cystine knot protein Noggin.

Authors:  Jay Groppe; Jason Greenwald; Ezra Wiater; Joaquin Rodriguez-Leon; Aris N Economides; Witek Kwiatkowski; Markus Affolter; Wylie W Vale; Juan Carlos Izpisua Belmonte; Senyon Choe
Journal:  Nature       Date:  2002-12-12       Impact factor: 49.962

Review 3.  Structural studies of the TGF-βs and their receptors - insights into evolution of the TGF-β superfamily.

Authors:  Andrew P Hinck
Journal:  FEBS Lett       Date:  2012-05-28       Impact factor: 4.124

Review 4.  Bone morphogenetic proteins: a critical review.

Authors:  Beth Bragdon; Oleksandra Moseychuk; Sven Saldanha; Daniel King; Joanne Julian; Anja Nohe
Journal:  Cell Signal       Date:  2010-10-16       Impact factor: 4.315

Review 5.  Smad transcription factors.

Authors:  Joan Massagué; Joan Seoane; David Wotton
Journal:  Genes Dev       Date:  2005-12-01       Impact factor: 11.361

6.  Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation.

Authors:  Vaclav Veverka; Alistair J Henry; Patrick M Slocombe; Andrew Ventom; Barbara Mulloy; Frederick W Muskett; Mariusz Muzylak; Kevin Greenslade; Adrian Moore; Li Zhang; Jianhua Gong; Xueming Qian; Chris Paszty; Richard J Taylor; Martyn K Robinson; Mark D Carr
Journal:  J Biol Chem       Date:  2009-02-10       Impact factor: 5.157

7.  Members of the DAN family are BMP antagonists that form highly stable noncovalent dimers.

Authors:  Chandramohan Kattamuri; David M Luedeke; Kristof Nolan; Scott A Rankin; Kenneth D Greis; Aaron M Zorn; Thomas B Thompson
Journal:  J Mol Biol       Date:  2012-10-09       Impact factor: 5.469

8.  The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding.

Authors:  Jennifer N Cash; Carlis A Rejon; Alexandra C McPherron; Daniel J Bernard; Thomas B Thompson
Journal:  EMBO J       Date:  2009-07-30       Impact factor: 11.598
  8 in total
  2 in total

1.  Comparative transcriptome profiling approach to glean virulence and immunomodulation-related genes of Fasciola hepatica.

Authors:  Orçun Haçarız; Mete Akgün; Pınar Kavak; Bayram Yüksel; Mahmut Şamil Sağıroğlu
Journal:  BMC Genomics       Date:  2015-05-09       Impact factor: 3.969

Review 2.  TGFβ, smooth muscle cells and coronary artery disease: a review.

Authors:  Emma L Low; Andrew H Baker; Angela C Bradshaw
Journal:  Cell Signal       Date:  2018-09-15       Impact factor: 4.315
  2 in total

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