Literature DB >> 23929823

A high-resolution structure that provides insight into coiled-coil thiodepsipeptide dynamic chemistry.

Zehavit Dadon1, Manickasundaram Samiappan, Anat Shahar, Raz Zarivach, Gonen Ashkenasy.   

Abstract

Stable and reactive: A crystal structure at 1.35 Å of a thioester coiled-coil protein reveals high similarity to all-peptide-bond proteins. In these assemblies, the thioester bonds are kept reactive towards thiol molecules in the mixture. This enables efficient domain exchange between proteins in response to changes in folding conditions or introduction of external templates.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  coiled coils; depsipeptides; dynamic chemistry; peptide networks; thiodepsipeptides

Mesh：

Substances：

Year:  2013        PMID： 23929823     DOI： 10.1002/anie.201303900

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  6 in total

1.  Water-Based Dynamic Depsipeptide Chemistry: Building Block Recycling and Oligomer Distribution Control Using Hydration-Dehydration Cycles.

Authors:  Martin C; Moran Frenkel-Pinter; Kelvin H Smith; Victor F Rivera-Santana; Alyssa B Sargon; Kaitlin C Jacobson; Aikomari Guzman-Martinez; Loren Dean Williams; Luke J Leman; Charles L Liotta; Martha A Grover; Nicholas V Hud
Journal:  JACS Au       Date:  2022-05-17

2.  Thioesters provide a plausible prebiotic path to proto-peptides.

Authors:  Moran Frenkel-Pinter; Marcos Bouza; Facundo M Fernández; Luke J Leman; Loren Dean Williams; Nicholas V Hud; Aikomari Guzman-Martinez
Journal:  Nat Commun       Date:  2022-05-11       Impact factor: 17.694

Review 3.  Analysis of folded structure and folding thermodynamics in heterogeneous-backbone proteomimetics.

Authors:  Jacqueline R Santhouse; Shilpa R Rao; W Seth Horne
Journal:  Methods Enzymol       Date:  2021-05-03       Impact factor: 1.600

4.  Self-Assembly Can Direct Dynamic Covalent Bond Formation toward Diversity or Specificity.

Authors:  Dávid Komáromy; Marc C A Stuart; Guillermo Monreal Santiago; Meniz Tezcan; Victor V Krasnikov; Sijbren Otto
Journal:  J Am Chem Soc       Date:  2017-04-24       Impact factor: 15.419

5.  A chemically fueled non-enzymatic bistable network.

Authors:  Indrajit Maity; Nathaniel Wagner; Rakesh Mukherjee; Dharm Dev; Enrique Peacock-Lopez; Rivka Cohen-Luria; Gonen Ashkenasy
Journal:  Nat Commun       Date:  2019-10-11       Impact factor: 14.919

6.  Selenopeptide transamidation and metathesis.

Authors:  Nathalie Ollivier; Annick Blanpain; Emmanuelle Boll; Laurent Raibaut; Hervé Drobecq; Oleg Melnyk
Journal:  Org Lett       Date:  2014-07-14       Impact factor: 6.005
  6 in total

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