OBJECTIVE: To determine differences in follicle stimulation, oocyte retrieval, maturation, and fertilization among patients who underwent bariatric surgery, obese patients, and patients with 18 < BMI < 30 kg/m² submitted to assisted reproduction techniques and check that these patients may have some impairment in ovarian response. METHODS: The study comprised three groups: GI: 29 patients who had undergone restrictive and/or malabsorptive bariatric surgery; GII: 57 obese patients (BMI > 30 kg/m²); and GIII: 94 patients (18 < BMI < 30 kg/m²) with infertility due to a male factor. BMI, weight loss until oocyte retrieval, vitamin supplementation, and anemia were evaluated. Data were compared with the number of follicles observed, the number of oocytes retrieved, and the maturation status of these oocytes. Results were analyzed statistically. RESULTS: A statistically significant difference in the number of follicles observed by ultrasound (P < 0.01), the number of oocytes retrieved (P = 0.013), and the number of metaphase II oocytes (P < 0.01) between the patients with prior bariatric surgery and both GII and GIII group was found. CONCLUSIONS: The weight loss resulting from bariatric surgery can be very beneficial to the overall health of the woman, but the reproductive process can be impaired. Bariatric surgery appears to have an important impact on the formation of follicles and oocytes.
OBJECTIVE: To determine differences in follicle stimulation, oocyte retrieval, maturation, and fertilization among patients who underwent bariatric surgery, obesepatients, and patients with 18 < BMI < 30 kg/m² submitted to assisted reproduction techniques and check that these patients may have some impairment in ovarian response. METHODS: The study comprised three groups: GI: 29 patients who had undergone restrictive and/or malabsorptive bariatric surgery; GII: 57 obesepatients (BMI > 30 kg/m²); and GIII: 94 patients (18 < BMI < 30 kg/m²) with infertility due to a male factor. BMI, weight loss until oocyte retrieval, vitamin supplementation, and anemia were evaluated. Data were compared with the number of follicles observed, the number of oocytes retrieved, and the maturation status of these oocytes. Results were analyzed statistically. RESULTS: A statistically significant difference in the number of follicles observed by ultrasound (P < 0.01), the number of oocytes retrieved (P = 0.013), and the number of metaphase II oocytes (P < 0.01) between the patients with prior bariatric surgery and both GII and GIII group was found. CONCLUSIONS: The weight loss resulting from bariatric surgery can be very beneficial to the overall health of the woman, but the reproductive process can be impaired. Bariatric surgery appears to have an important impact on the formation of follicles and oocytes.
Authors: Randi H Goldman; Stacey A Missmer; Malcolm K Robinson; Leslie V Farland; Elizabeth S Ginsburg Journal: Obes Surg Date: 2016-11 Impact factor: 4.129
Authors: Marco Milone; Loredana M Sosa Fernandez; Laura V Sosa Fernandez; Michele Manigrasso; Ugo Elmore; Giovanni D De Palma; Mario Musella; Francesco Milone Journal: Obes Surg Date: 2017-08 Impact factor: 4.129
Authors: V Grzegorczyk-Martin; T Fréour; A De Bantel Finet; E Bonnet; M Merzouk; J Roset; V Roger; I Cédrin-Durnerin; R Wainer; C Avril; P Landais Journal: Hum Reprod Date: 2020-12-01 Impact factor: 6.918
Authors: Katinka M Snoek; Régine P M Steegers-Theunissen; Eric J Hazebroek; Sten P Willemsen; Sander Galjaard; Joop S E Laven; Sam Schoenmakers Journal: Hum Reprod Update Date: 2021-10-18 Impact factor: 15.610