Literature DB >> 23928507

Is green tea a potential trigger for autoimmune hepatitis?

Eugenia Gallo1, Valentina Maggini, Margherita Berardi, Alessandra Pugi, Rosario Notaro, Giulia Talini, Giancarlo Vannozzi, Siro Bagnoli, Paolo Forte, Alessandro Mugelli, Vito Annese, Fabio Firenzuoli, Alfredo Vannacci.   

Abstract

A case of autoimmune liver hepatitis is reported: the onset was triggered by consumption of green tea infusion in a patient taking oral contraceptives and irbesartan. We hypothesize that our patient, carrying genetic variant of hepatic metabolism making her particularly susceptible to oxidative stress, developed an abnormal response to a mild toxic insult, afforded by a combination of agents (oral contraceptives+irbesartan+green tea) that normally would not be able to cause damage. Her particular hepatic metabolism further increased the drugs' concentration, favoring the haptenization of liver proteins, eventually leading to the development of an autoimmune hepatitis.
Copyright © 2013 Elsevier GmbH. All rights reserved.

Entities:  

Keywords:  AIH; ALT; AP; Autoimmune hepatitis; CYP; Catechin; EGCG; GGT; GST; Green tea; MDR; MTHFR; SULT; Single nucleotide polymorphism; UDP glucuronosyltransferase; UGT; alanine aminotransferase; alkaline phosphatase; autoimmune like hepatitis; cytochrome P450; epigallocatechin-3-gallate; glutamiltransferase; glutathione S-transferase; methylenetetrahydrofolate reductase; multidrug resistance; sulfotransferase

Mesh:

Substances:

Year:  2013        PMID: 23928507     DOI: 10.1016/j.phymed.2013.07.004

Source DB:  PubMed          Journal:  Phytomedicine        ISSN: 0944-7113            Impact factor:   5.340


  7 in total

1.  Chinese green tea and acute hepatitis: a rare yet recurring theme.

Authors:  Sebastian Thomas Lugg; Darryl Braganza Menezes; Simon Gompertz
Journal:  BMJ Case Rep       Date:  2015-09-23

Review 2.  Acute liver injury following Garcinia cambogia weight-loss supplementation: case series and literature review.

Authors:  Giada Crescioli; Niccolò Lombardi; Alessandra Bettiol; Ettore Marconi; Filippo Risaliti; Michele Bertoni; Francesca Menniti Ippolito; Valentina Maggini; Eugenia Gallo; Fabio Firenzuoli; Alfredo Vannacci
Journal:  Intern Emerg Med       Date:  2018-05-25       Impact factor: 3.397

3.  Green Tea Extract-induced Acute Hepatotoxicity in Rats.

Authors:  Yuko Emoto; Katsuhiko Yoshizawa; Yuichi Kinoshita; Michiko Yuki; Takashi Yuri; Yutaka Yoshikawa; Kazutoshi Sayama; Airo Tsubura
Journal:  J Toxicol Pathol       Date:  2014-05-26       Impact factor: 1.628

Review 4.  Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics.

Authors:  Miren García-Cortés; Mercedes Robles-Díaz; Aida Ortega-Alonso; Inmaculada Medina-Caliz; Raul J Andrade
Journal:  Int J Mol Sci       Date:  2016-04-09       Impact factor: 5.923

Review 5.  United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts.

Authors:  Hellen A Oketch-Rabah; Amy L Roe; Cynthia V Rider; Herbert L Bonkovsky; Gabriel I Giancaspro; Victor Navarro; Mary F Paine; Joseph M Betz; Robin J Marles; Steven Casper; Bill Gurley; Scott A Jordan; Kan He; Mahendra P Kapoor; Theertham P Rao; Averell H Sherker; Robert J Fontana; Simona Rossi; Raj Vuppalanchi; Leonard B Seeff; Andrew Stolz; Jawad Ahmad; Christopher Koh; Jose Serrano; Tieraona Low Dog; Richard Ko
Journal:  Toxicol Rep       Date:  2020-02-15

Review 6.  Antioxidant, Anti-Inflammatory, and Immunomodulatory Properties of Tea-The Positive Impact of Tea Consumption on Patients with Autoimmune Diabetes.

Authors:  Anna Winiarska-Mieczan; Ewa Tomaszewska; Karolina Jachimowicz
Journal:  Nutrients       Date:  2021-11-07       Impact factor: 5.717

7.  Herb-induced liver injury: Systematic review and meta-analysis.

Authors:  Vinícius Remus Ballotin; Lucas Goldmann Bigarella; Ajacio Bandeira de Mello Brandão; Raul Angelo Balbinot; Silvana Sartori Balbinot; Jonathan Soldera
Journal:  World J Clin Cases       Date:  2021-07-16       Impact factor: 1.337

  7 in total

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