| Literature DB >> 23926944 |
A Requena-Méndez1, P Goñi, S Lóbez, I Oliveira, E Aldasoro, M-E Valls, A Clavel, J Gascón, J Muñoz.
Abstract
Persistence of giardiasis after some of the recommended drugs is occurring with increasing frequency. We describe the follow-up of four members of a family with giardiasis through microscopic observation, immunochromatography and PCRs of tpi and β-giardin genes. Three patients did not respond to tinidazole but they were cured after quinacrine. However, PCR became negative at 2 months after negativization of stools in two patients and after 1 year in one patient. In all cases Giardia assemblage B was characterized with high homology between all isolates. Further studies are needed to determine the value of PCR in the diagnosis of Giardia infections.Entities:
Keywords: Giardia; nitroimidazole; polymerase chain reaction; quinacrine; refractory giardiasis
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Year: 2013 PMID： 23926944 DOI： 10.1111/1469-0691.12327
Source DB: PubMed Journal: Clin Microbiol Infect ISSN： 1198-743X Impact factor: 8.067