Literature DB >> 23925926

The effect of a Rapid Access Prostate Cancer Clinic on prostate cancer patient and disease characteristics, primary treatment and surgical workload.

S F Oon1, I M Cullen, D Moran, E M Bolton, T McDermott, R Grainger, T H Lynch.   

Abstract

BACKGROUND: In 2009, Rapid Access Prostate Cancer Clinics (RAPC) were introduced to St. James's Hospital to improve the access and organisation of patients to prostate cancer investigations and treatment. AIMS: To observe the effects of the RAPC on prostate cancer diagnosis, primary treatment and overall workload.
METHODS: Using a prospectively designed patient database, the records of all prostate cancer patients between 2007 and 2011 were retrieved and analysed. Data were obtained for age, PSA, biopsy Gleason score and primary treatment modality and charted for the observation and comparison of trends.
RESULTS: Seven hundred and eighty-nine patients had a new diagnosis of prostate cancer between 2007 and 2011. The median PSA prior to the RAPC was 9.7-13.1 ng/ml, which decreased to 7.79-9 ng/ml after the RAPC. Prior to the RAPC, 77-81 biopsies were performed annually versus 149-271 in the post-RAPC era. Annual requirements for radical prostatectomy also increased from 12 to 27 in the post-RAPC era. Conversely, an initially increasing percentage of patients for radiotherapy was reversed in the post-RAPC period. An increasing trend for higher grade PCa (Gleason score 4 + 4 and higher) was also reversed.
CONCLUSIONS: The introduction of a RAPC improves the overall pathological characteristics of patients with prostate cancer. However, RAPCs are also associated with a considerable increase in surgical workload. These are important considerations for units considering the incorporation of a similar facility in their institutions.

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Year:  2013        PMID: 23925926     DOI: 10.1007/s11845-013-0997-8

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  6 in total

Review 1.  The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma.

Authors:  Jonathan I Epstein; William C Allsbrook; Mahul B Amin; Lars L Egevad
Journal:  Am J Surg Pathol       Date:  2005-09       Impact factor: 6.394

2.  Can delayed time to referral to a tertiary level urologist with an abnormal PSA level affect subsequent Gleason grade in the opportunistically screened population?

Authors:  Fardod O'Kelly; Arun Thomas; Denise Murray; David Galvin; David Mulvin; David M Quinlan
Journal:  Prostate       Date:  2013-05-08       Impact factor: 4.104

3.  Emerging evidence for Gleason grade migration and distance impact in prostate cancer? An analysis of the rapid access prostate clinic in a tertiary referral center: St. Vincent's University Hospital, Dublin (2009-2011).

Authors:  F O'Kelly; A Z Thomas; D Murray; P Lee; R F O'Carroll; P Nicholson; H Forristal; N Swan; D Galvin; D Mulvin; D M Quinlan
Journal:  Ir J Med Sci       Date:  2013-02-17       Impact factor: 1.568

4.  A rapid access diagnostic clinic for prostate cancer: the experience after one year.

Authors:  J C Forde; K M O'Connor; L Casey; M O'Brien; S Bowen; R G Casey; I Ahmed; T E McDermott; R Grainger; T H Lynch
Journal:  Ir J Med Sci       Date:  2011-02-04       Impact factor: 1.568

5.  Cancer surveillance series: interpreting trends in prostate cancer--part I: Evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival rates.

Authors:  B F Hankey; E J Feuer; L X Clegg; R B Hayes; J M Legler; P C Prorok; L A Ries; R M Merrill; R S Kaplan
Journal:  J Natl Cancer Inst       Date:  1999-06-16       Impact factor: 13.506

Review 6.  An update of the Gleason grading system.

Authors:  Jonathan I Epstein
Journal:  J Urol       Date:  2009-12-14       Impact factor: 7.450

  6 in total
  2 in total

1.  The effect of Rapid Access Prostate Clinics on the outcomes of Gleason 7 prostate cancer: does earlier diagnosis lead to better outcomes?

Authors:  M P Broe; J C Forde; M S Inder; D J Galvin; D W Mulvin; D M Quinlan
Journal:  Ir J Med Sci       Date:  2017-03-09       Impact factor: 1.568

2.  How do the characteristics of breast cancer diagnostic assessment programmes influence service delivery: A mixed methods study.

Authors:  A R Gagliardi; G Honein-AbouHaidar; T Stuart-McEwan; J Smylie; A Arnaout; J Seely; F C Wright; M J Dobrow; M C Brouwers; K Bukhanov; D R McCready
Journal:  Eur J Cancer Care (Engl)       Date:  2017-06-21       Impact factor: 2.520

  2 in total

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