Literature DB >> 23923757

[Neurosurgical treatment of chronic pain].

Denys Fontaine1.   

Abstract

Neurosurgical treatment of pain is based on 3 concepts: 1) lesional techniques interrupt the transmission of nociceptive neural input by lesionning the nociceptive pathways (cordotomy, radicotomy...), they are indicated to treat morphine-resistant cancer pain; 2) neuromodulation techniques try to decrease pain by reinforcing inhibitory mechanisms, using chronic electrical stimulation of the nervous system (peripheral nerve stimulation, spinal cord stimulation, motor cortex stimulation...) to treat chronic neuropathic pain; 3) intrathecal infusion of analgesics (morphine, ziconotide), using implantable pumps, allows to increase their efficacy and to reduce their side effects. These techniques can improve, sometimes dramatically, patients with severe and chronic pain, refractory to all other treatments.

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Year:  2013        PMID: 23923757

Source DB:  PubMed          Journal:  Rev Prat        ISSN: 0035-2640


  1 in total

1.  Epidural Spinal Cord Stimulation Promotes Motor Functional Recovery by Enhancing Oligodendrocyte Survival and Differentiation and by Protecting Myelin after Spinal Cord Injury in Rats.

Authors:  Gang Li; Zhong-Kai Fan; Guang-Fei Gu; Zhi-Qiang Jia; Qiang-Qiang Zhang; Jun-Yu Dai; Shi-Sheng He
Journal:  Neurosci Bull       Date:  2019-11-16       Impact factor: 5.203

  1 in total

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