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Literature DB >> 23921789

[Antidotes in clinical toxicology].

Abstract

This overview describes antidotes, and their clinical pharmacology, that have an established significance in the currently practiced clinical toxicology because of their proven effectiveness in the treatment of serious poisonings. For the proper, efficient, and targeted use of an antidote, pharmacological knowledge is required, which is a central subject of this article. Current data from the literature are used as reference along with the accumulated experiences about possible adverse effects in order to include them in therapeutic considerations. The dosage of antidotes is the subject of several other review articles and is therefore not included in this synopsis.

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Year: 2013 PMID： 23921789 DOI： 10.1007/s00063-013-0221-7

Source DB: PubMed Journal: Med Klin Intensivmed Notfmed ISSN： 2193-6218 Impact factor: 0.840

12 in total

1. Failure of lipid emulsion to reverse neurotoxicity after an ultrasound-guided axillary block with ropivacaine and mepivacaine.

Authors: Emile Calenda; Stelian A Dinescu
Journal: J Anesth Date: 2009-08-14 Impact factor: 2.078

2. [Cardiogenic shock after drug therapy for atrial fibrillation with tachycardia : Case report of an 89-year-old woman].

Authors: H Fey; M Jost; A T Geise; T Bertsch; M Christ
Journal: Med Klin Intensivmed Notfmed Date: 2015-10-06 Impact factor: 0.840

2 in total

[Antidotes in clinical toxicology].

1. Failure of lipid emulsion to reverse neurotoxicity after an ultrasound-guided axillary block with ropivacaine and mepivacaine.

2. Lipid infusion therapy: translation to clinical practice.

Review 3. Lipid emulsion infusion: resuscitation for local anesthetic and other drug overdose.

4. Fomepizole may change indication for hemodialysis in methanol poisoning: prospective study in seven cases.

5. Somatostatin inhibits B-cell secretion via a subtype-2 somatostatin receptor in the isolated perfused human pancreas.

6. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study.

7. Haemodynamic effects of high doses of insulin during acute left ventricular failure in dogs.

Review 8. Lipid emulsions in the treatment of acute poisoning: a systematic review of human and animal studies.

9. Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine.

10. High-dose insulin: a consecutive case series in toxin-induced cardiogenic shock.

1. [Acute poisoning in adults].

2. [Cardiogenic shock after drug therapy for atrial fibrillation with tachycardia : Case report of an 89-year-old woman].