Literature DB >> 23921146

Response to the letter to the editor by Susan Thorpe et al.: how predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response.

Babette Wolf1, Hannah Morgan, Frank Brennan, Jennifer Krieg, Zaahira Gani, Stewart Jones, Andrea Kiessling.   

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Year:  2013        PMID: 23921146     DOI: 10.1016/j.cyto.2013.07.014

Source DB:  PubMed          Journal:  Cytokine        ISSN: 1043-4666            Impact factor:   3.861


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  1 in total

1.  Cytokine release assays for the prediction of therapeutic mAb safety in first-in man trials--Whole blood cytokine release assays are poorly predictive for TGN1412 cytokine storm.

Authors:  S Vessillier; D Eastwood; B Fox; J Sathish; S Sethu; T Dougall; S J Thorpe; R Thorpe; R Stebbings
Journal:  J Immunol Methods       Date:  2015-05-07       Impact factor: 2.303

  1 in total

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