Literature DB >> 2391952

Correlation of blood pressure in end-stage renal disease with platelet cytosolic free-calcium concentration.

H Schiffl1.   

Abstract

The fluorescent probe Quin-2 showed the cytosolic free-calcium concentration in platelets to be elevated in 12 hypertensive hemodialysis patients, who were compared with 12 normotensive hemodialysis patients. There was a close correlation between the free-calcium level of platelets and mean arterial pressure (r = 0.88). Short-term antihypertensive treatment resulted in a reduction of free-calcium concentration and a concomitant fall in blood pressure. These results suggest an integrative contributory role for calcium in the pathophysiology of hypertension accompanying end-stage renal disease.

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Year:  1990        PMID： 2391952     DOI： 10.1007/bf01647579

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  26 in total

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Journal:  Kidney Int       Date:  1976-03       Impact factor: 10.612

2.  Platelet cytosolic free calcium concentration in hypertension associated with early stage kidney disease.

Authors:  H Schiffl
Journal:  Klin Wochenschr       Date:  1989-07-03

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Journal:  J Clin Endocrinol Metab       Date:  1969-10       Impact factor: 5.958

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Journal:  Lancet       Date:  1973-03-31       Impact factor: 79.321

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Journal:  Ann Intern Med       Date:  1972-05       Impact factor: 25.391

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Authors:  P Erne; P Bolli; E Bürgisser; F R Bühler
Journal:  N Engl J Med       Date:  1984-04-26       Impact factor: 91.245

Review 7.  Calcium-entry blockers, vascular smooth muscle and systemic hypertension.

Authors:  P M Vanhoutte
Journal:  Am J Cardiol       Date:  1985-01-25       Impact factor: 2.778

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Authors:  R Y Tsien; T Pozzan; T J Rink
Journal:  J Cell Biol       Date:  1982-08       Impact factor: 10.539

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Journal:  J Clin Endocrinol Metab       Date:  1988-08       Impact factor: 5.958

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Authors:  W Zidek; C Spieker; H Vetter
Journal:  J Hypertens       Date:  1986-08       Impact factor: 4.844
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  3 in total

1.  Modulation of platelet Ca2+ homeostasis by hypertensive plasma factor(s) derived from patients with early-stage renal disease.

Authors:  H Schiffl
Journal:  Klin Wochenschr       Date:  1991-12-11

Review 2.  [Thrombocytopathy and blood complications in uremia].

Authors:  Walter H Hörl
Journal:  Wien Klin Wochenschr       Date:  2006-04       Impact factor: 1.704

Review 3.  Hypertension in hemodialysis patients.

Authors:  M Rahman; M C Smith
Journal:  Curr Hypertens Rep       Date:  2001-12       Impact factor: 5.369
  3 in total

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