Literature DB >> 23918992

Kinase detection with gallium nitride based high electron mobility transistors.

Matthew S Makowski1, Isaac Bryan, Zlatko Sitar, Consuelo Arellano, Jinqiao Xie, Ramon Collazo, Albena Ivanisevic.   

Abstract

A label-free kinase detection system was fabricated by the adsorption of gold nanoparticles functionalized with kinase inhibitor onto AlGaN/GaN high electron mobility transistors (HEMTs). The HEMTs were operated near threshold voltage due to the greatest sensitivity in this operational region. The Au NP/HEMT biosensor system electrically detected 1 pM SRC kinase in ionic solutions. These results are pertinent to drug development applications associated with kinase sensing.

Entities:  

Year:  2013        PMID： 23918992      PMCID： PMC3716718          DOI： 10.1063/1.4812987

Source DB:  PubMed          Journal:  Appl Phys Lett        ISSN： 0003-6951            Impact factor:   3.791


  8 in total

1.  Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.

Authors:  Marcus Bantscheff; Dirk Eberhard; Yann Abraham; Sonja Bastuck; Markus Boesche; Scott Hobson; Toby Mathieson; Jessica Perrin; Manfred Raida; Christina Rau; Valérie Reader; Gavain Sweetman; Andreas Bauer; Tewis Bouwmeester; Carsten Hopf; Ulrich Kruse; Gitte Neubauer; Nigel Ramsden; Jens Rick; Bernhard Kuster; Gerard Drewes
Journal:  Nat Biotechnol       Date:  2007-08-26       Impact factor: 54.908

2.  Src family kinases are necessary for cell migration induced by extracellular HMGB1.

Authors:  Roberta Palumbo; Francesco De Marchis; Tobias Pusterla; Antonio Conti; Massimo Alessio; Marco E Bianchi
Journal:  J Leukoc Biol       Date:  2009-04-28       Impact factor: 4.962

3.  Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

Authors:  Henrik Daub; Jesper V Olsen; Michaela Bairlein; Florian Gnad; Felix S Oppermann; Roman Körner; Zoltán Greff; György Kéri; Olaf Stemmann; Matthias Mann
Journal:  Mol Cell       Date:  2008-08-08       Impact factor: 17.970

Review 4.  The hunting of the Src.

Authors:  G S Martin
Journal:  Nat Rev Mol Cell Biol       Date:  2001-06       Impact factor: 94.444

5.  Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors.

Authors:  Josef Wissing; Klaus Godl; Dirk Brehmer; Stephanie Blencke; Martina Weber; Peter Habenberger; Matthias Stein-Gerlach; Andrea Missio; Matt Cotten; Stefan Müller; Henrik Daub
Journal:  Mol Cell Proteomics       Date:  2004-10-08       Impact factor: 5.911

6.  Physisorption of functionalized gold nanoparticles on AlGaN/GaN high electron mobility transistors for sensing applications.

Authors:  M S Makowski; S Kim; M Gaillard; D Janes; M J Manfra; I Bryan; Z Sitar; C Arellano; J Xie; R Collazo; A Ivanisevic
Journal:  Appl Phys Lett       Date:  2013-02-19       Impact factor: 3.791

7.  Detection of clinically relevant levels of protein analyte under physiologic buffer using planar field effect transistors.

Authors:  Samit Gupta; Mark Elias; Xuejin Wen; John Shapiro; Leonard Brillson; Wu Lu; Stephen Craig Lee
Journal:  Biosens Bioelectron       Date:  2008-06-08       Impact factor: 10.618

8.  Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.

Authors:  James S Duncan; Martin C Whittle; Kazuhiro Nakamura; Amy N Abell; Alicia A Midland; Jon S Zawistowski; Nancy L Johnson; Deborah A Granger; Nicole Vincent Jordan; David B Darr; Jerry Usary; Pei-Fen Kuan; David M Smalley; Ben Major; Xiaping He; Katherine A Hoadley; Bing Zhou; Norman E Sharpless; Charles M Perou; William Y Kim; Shawn M Gomez; Xin Chen; Jian Jin; Stephen V Frye; H Shelton Earp; Lee M Graves; Gary L Johnson
Journal:  Cell       Date:  2012-04-13       Impact factor: 41.582
  8 in total

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