Literature DB >> 23918350

Intraocular malignant melanoma of the choroid presenting as orbital cellulitis.

Akshay Gopinathan Nair1, Swathi Kaliki, Mohammed Javed Ali, Milind N Naik, Geeta K Vemuganti.   

Abstract

We report a case of choroidal melanoma with features suggestive of orbital cellulitis. A 24-year-old Asian Indian male presented with a 20-day history of sudden loss of vision in the right eye. Edematous eyelids with complete mechanical ptosis, complete ophthalmoplegia, gross proptosis accompanied by massive chemosis, and prolapse of the inferior forniceal conjunctiva were noted. He denied perception of light in the right eye. The left eye was unremarkable. B-scan ultrasonography of the right eye showed a large dome-shaped mass filling the posterior segment suggestive of choroidal melanoma. Computed tomography confirmed those findings and showed no extraocular tumor extension. The patient was conservatively treated with systemic steroids following which the inflammation subsided. He underwent enucleation of the right eye and a diagnosis of spindle A cell choroidal melanoma was confirmed by histopathological examination. Although rare, orbital cellulitis is one of the presenting features of choroidal melanoma. Uveal melanoma-associated orbital cellulitis can be well controlled with systemic steroids, does not always indicate extraocular tumor extension, and can occur in spindle A cell melanomas.

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Year:  2013        PMID: 23918350     DOI: 10.1007/s10792-013-9836-1

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  5 in total

1.  Presenting signs and symptoms of choroidal melanoma: what do they mean?

Authors:  C A Servodidio; D H Abramson
Journal:  Ann Ophthalmol       Date:  1992-05

2.  Malignant melanoma of the choroid presenting as orbital cellulitis: report of two cases with a review of the literature.

Authors:  Jyotirmay Biswas; Vijay K. Ahuja; Mahesh P. Shanmugam; Rangini Kurian; Tony Fernandez
Journal:  Orbit       Date:  1999-06

3.  Orbital melanoma presenting as orbital cellulitis: a clinicopathologic report.

Authors:  J Fezza; I A Chaudhry; Y H Kwon; E E Grannum; J Sinard; D E Wolfley
Journal:  Ophthalmic Plast Reconstr Surg       Date:  1998-07       Impact factor: 1.746

4.  Necrotic malignant melanomas of the choroid and ciliary body. A clinicopathological and statistical study.

Authors:  K Bujara
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1982       Impact factor: 3.117

5.  Histopathologic characteristics of uveal melanomas in eyes enucleated from the Collaborative Ocular Melanoma Study. COMS report no. 6.

Authors: 
Journal:  Am J Ophthalmol       Date:  1998-06       Impact factor: 5.258

  5 in total
  3 in total

1.  Orbital Cellulitis and Secondary Angle Closure: A Rare Presentation of Choroidal Melanoma.

Authors:  Lawrence J Oh; Hamish Dunn; Svetlana Cherepanoff; Michel Giblin
Journal:  Ocul Oncol Pathol       Date:  2017-09-26

Review 2.  Necrotic Uveal Melanoma Mimics Orbital Cellulitis: A Review.

Authors:  Ahmad Abdel-Aty; Wendy L Linderman; Ninani Kombo; John Sinard; Renelle Pointdujour-Lim
Journal:  Ocul Oncol Pathol       Date:  2021-11-23

3.  Necrotic uveal melanoma presenting as orbital cellulitis with intraocular hemorrhage: A case report.

Authors:  Alexa L Li; Julia Y Kang; Duncan E Berry; Krishna B Patel; Andrew M Hendrick
Journal:  Am J Ophthalmol Case Rep       Date:  2019-09-25
  3 in total

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