Literature DB >> 23916804

Octogenarians with uncomplicated acute type a aortic dissection benefit from emergency operation.

Alessandro Piccardo1, Alexandre Le Guyader, Tommaso Regesta, Vlad Gariboldi, Konstantinos Zannis, Michel Tapia, Frederic Collart, Matthias Kirsch, Thierry Caus, Elisabeth Cornu, Marc Laskar.   

Abstract

BACKGROUND: The management of acute type A aortic dissection (aTAAD) in octogenarian patients is controversial. This study analyzed the surgical outcomes to identify patients who should undergo operations.
METHODS: Beginning in January 2000, we established a registry including all octogenarian patients operated on for type A acute aortic dissection. We evaluated 79 consecutive patients enrolled up to December 2010. Their median age was 81.6 years (range, 80 to 89 years). Sixteen patients (20%) presented a complicated type because of a neurologic deficit, mesenteric ischemia, a requirement for cardiopulmonary resuscitation, or some combination of those features. Operations followed the standard procedure recommended for younger patients. Follow-up was 95% complete (mean, 4.6±2.8 years).
RESULTS: The overall in-hospital mortality was 44.3%. The in-hospital mortality among patients with uncomplicated aTAAD was 33.3%. Multivariate analysis identified complicated aTAAD as the only risk factors for in-hospital mortality (p<0.0001). Postoperative complications occurred in 50 patients (68.5%) and were associated with a higher mortality (p<0.0001). The overall survival was 53% at 1 year and 32% at 5 years. In uncomplicated aTAAD, the overall survival was 63% at 1 year and 38% at 5 years.
CONCLUSIONS: Octogenarians with uncomplicated aTAAD benefit from emergency surgical repair. In those patients, early and midterm outcomes are good and are similar to those in published series of younger patients. Complicated aTAAD should be medically managed.
Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  26

Mesh:

Year:  2013        PMID: 23916804     DOI: 10.1016/j.athoracsur.2013.04.066

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  10 in total

Review 1.  Emergent aortic surgery in octogenarians: is the advanced age a contraindication?

Authors:  Mario Castaño; Javier Gualis; Jose M Martínez-Comendador; Elio Martín; Pasquale Maiorano; Laura Castillo
Journal:  J Thorac Dis       Date:  2017-05       Impact factor: 2.895

Review 2.  Clinical dilemma in the surgical treatment of organ malperfusion caused by acute type A aortic dissection.

Authors:  Takeshi Shimamoto; Tatsuhiko Komiya
Journal:  Gen Thorac Cardiovasc Surg       Date:  2014-04-26

3.  Svensson class IV Ascending aortic dissection, often confused with penetrating ulcer.

Authors:  Michel Francklyn Mitsomoy; Valerica Alexoiu; Matthias Kirsch
Journal:  J Cardiovasc Thorac Res       Date:  2015-03-29

4.  Vascular disease in the older adult.

Authors:  Andrew P Miller; Christopher M Huff; Gary S Roubin
Journal:  J Geriatr Cardiol       Date:  2016-09       Impact factor: 3.327

5.  The future of stenting in patients with type A aortic dissection: a systematic review.

Authors:  Amer Harky; Jeremy Chan; Beverly MacCarthy-Ofosu
Journal:  J Int Med Res       Date:  2019-09-12       Impact factor: 1.671

Review 6.  Outcomes of surgery for acute type A dissection in octogenarians versus non-octogenarians: a systematic review and meta analysis.

Authors:  Aditya Eranki; Michael Merakis; Michael L Williams; Campbell D Flynn; Claudia Villanueva; Ashley Wilson-Smith; Yangsin Lee; Ross Mejia
Journal:  J Cardiothorac Surg       Date:  2022-09-01       Impact factor: 1.522

7.  Age, sex, and contemporary outcomes in surgical repair of type A aortic dissection: Insights from the National Inpatient Sample.

Authors:  Michael A Catalano; Tania Mamdouhi; Stevan Pupovac; Kevin F Kennedy; Derek R Brinster; Alan Hartman; Pey-Jen Yu
Journal:  JTCVS Open       Date:  2022-06-23

Review 8.  Surgical repair of Stanford type A aortic dissection in elderly patients: a contemporary systematic review and meta-analysis.

Authors:  Vito D Bruno; Pierpaolo Chivasso; Gustavo Guida; Hunaid A Vohra
Journal:  Ann Cardiothorac Surg       Date:  2016-07

9.  Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: a 13-year institutional experience.

Authors:  Chun-Yu Lin; Lai-Chu See; Chi-Nan Tseng; Meng-Yu Wu; Yi Han; Cheng-Hui Lu; Feng-Chun Tsai
Journal:  Sci Rep       Date:  2020-09-10       Impact factor: 4.379

10.  Outcomes of Acute Aortic Dissection Surgery in Octogenarians.

Authors:  Ming-En Hsu; An-Hsun Chou; Yu-Ting Cheng; Hsiu-An Lee; Kuo-Sheng Liu; Dong-Yi Chen; Victor Chien-Chia Wu; Pao-Hsien Chu; Tien-Hsing Chen; Shao-Wei Chen
Journal:  J Am Heart Assoc       Date:  2020-09-11       Impact factor: 5.501

  10 in total

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