Mayowa O Owolabi1, Atinuke M Agunloye. 1. Department of Medicine, University College Hospital, Ibadan, 200001 Oyo State, Nigeria; College of Medicine, University of Ibadan. Nigeria. Electronic address: mayowaowolabi@yahoo.com.
Abstract
OBJECTIVE: To comprehensively examine the relationship of vascular risk factors to stroke type in native black Africans. METHODS: We explored 34 candidate demographic, clinical, and laboratory variables in 282 consecutive adult stroke patients with brain imaging. RESULTS: Ischemic stroke (IS) was found in 61.7% (174). Gender, alcohol, cigarette, homocysteine, C-reactive peptide, anthropometry, and carotid parameters were not significantly associated with stroke type (p>0.05). Patients with IS had relatively lower BP, were significantly older, and more frequently had diabetes mellitus, cardiac disease, or previous transient ischemic attack than patients with hemorrhagic stroke (HS). However, in multivariate regression model predicting 69% of stroke type correctly, age≥62 years (OR: 4.0, 95% CI: 2.0-7.9), previous TIA (OR: 4.3, 95% CI: 1.2-15.7) and systolic BP≥140 mmHg (OR: 0.4, 95% CI: 0.2-0.9) were the only independent significant predictors of IS. CONCLUSIONS: With increasing proportion of the population over 61 years and better BP control, the proportion of IS is expected to rise in black African countries currently undergoing epidemiological transition (changing lifestyle/disease pattern). Therefore, relevant components of the stroke intervention quadrangle (stroke surveillance, acute care, preventive and rehabilitation services) should be tailored toward this need.
OBJECTIVE: To comprehensively examine the relationship of vascular risk factors to stroke type in native black Africans. METHODS: We explored 34 candidate demographic, clinical, and laboratory variables in 282 consecutive adult strokepatients with brain imaging. RESULTS:Ischemic stroke (IS) was found in 61.7% (174). Gender, alcohol, cigarette, homocysteine, C-reactive peptide, anthropometry, and carotid parameters were not significantly associated with stroke type (p>0.05). Patients with IS had relatively lower BP, were significantly older, and more frequently had diabetes mellitus, cardiac disease, or previous transient ischemic attack than patients with hemorrhagic stroke (HS). However, in multivariate regression model predicting 69% of stroke type correctly, age≥62 years (OR: 4.0, 95% CI: 2.0-7.9), previous TIA (OR: 4.3, 95% CI: 1.2-15.7) and systolic BP≥140 mmHg (OR: 0.4, 95% CI: 0.2-0.9) were the only independent significant predictors of IS. CONCLUSIONS: With increasing proportion of the population over 61 years and better BP control, the proportion of IS is expected to rise in black African countries currently undergoing epidemiological transition (changing lifestyle/disease pattern). Therefore, relevant components of the stroke intervention quadrangle (stroke surveillance, acute care, preventive and rehabilitation services) should be tailored toward this need.
Authors: Solveig A Cunningham; Aleena Mosher; Suzanne E Judd; Lisa M Matz; Edmond K Kabagambe; Claudia S Moy; Virginia J Howard Journal: J Gerontol B Psychol Sci Soc Sci Date: 2018-04-16 Impact factor: 4.077
Authors: Ahmed Solomon; Linda Tsang; Angela J Woodiwiss; Aletta M E Millen; Gavin R Norton; Patrick H Dessein Journal: Biomed Res Int Date: 2014-07-23 Impact factor: 3.411
Authors: Eric S Donkor; Mayowa O Owolabi; Patrick O Bampoh; Philip K Amoo; Thor Aspelund; Vilmundur Gudnason Journal: Clin Interv Aging Date: 2014-10-08 Impact factor: 4.458
Authors: Gertrude Namale; Onesmus Kamacooko; Alison Kinengyere; Laetitia Yperzeele; Patrick Cras; Edward Ddumba; Janet Seeley; Robert Newton Journal: J Trop Med Date: 2018-05-31