Literature DB >> 23916387

Integra™ permits early durable coverage of improvised explosive device (IED) amputation stumps.

Deborah P S Foong1, Demetrius Evriviades, Steven L A Jeffery.   

Abstract

INTRODUCTION: Improvised explosive device (IED) blasts cause serious injury. Survivors are left with multiple amputations, considerable soft tissue loss and open fractures with gross contamination. We present our early experience of Integra™ in the acute management of military wounds.
METHOD: The clinical records of all patients with IED injuries who underwent early reconstruction with Integra™ during the six month period between August and December 2009 in our unit were reviewed and data gathered prospectively.
RESULTS: There were 7 male soldiers, aged 21-31 years (mean=26). All sustained trunk and limb injuries, including multiple amputations. Number of procedures prior to application of Integra™ was 4-10 (mean=5). Application of Integra™ took place 6-24 days post-injury (mean=13). Size of wounds covered with Integra™ was 1-11.5% TBSA (mean=5%). Anatomical sites reconstructed included amputation stumps, and both upper and lower limbs. There was partial take of Integra in 3 wounds in 2 patients. All wounds were eventually treated with delayed split skin grafting and healed satisfactorily.
CONCLUSION: IEDs produce a large zone of injury with massive soft tissue damage, multiple discontinuous wounds which are significantly contaminated. The physiological insult is equivalent to a large cutaneous burn and there is a paucity of available donor sites. Multiple amputees also have a greater energy and power requirement(1-4) and cannot spare remaining functional muscles as donors. The literature suggests that microvascular flaps have a high failure rate in military patients.(5) Reconstruction began as soon as wounds were considered sufficiently clean. Integra™ was applied with the aim of providing higher quality coverage than that provided by split skin grafting alone (particularly for amputation stumps) whilst minimising operative time and morbidity. Integra™ allows timely closure of battlefield wounds with minimal operative time and morbidity. The procedure can begin whilst still in the acute phase and certainly before one would consider lengthy complex operations such as free flaps. Our experience suggests that Integra™ can allow early closure with robust tissue, promoting early rehabilitation and return to duties.
Copyright © 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Amputation; Ballistic; Battle wounds; Blast; Dermal substitute; Improvised explosive device; Injury; Integra; Soft tissue reconstruction; Stump

Mesh:

Substances:

Year:  2013        PMID: 23916387     DOI: 10.1016/j.bjps.2013.07.007

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  6 in total

1.  Soft tissue and wound management of blast injuries.

Authors:  Andrew J Sheean; Scott M Tintle; Peter C Rhee
Journal:  Curr Rev Musculoskelet Med       Date:  2015-09

Review 2.  The Management of Combat Wounds: The British Military Experience.

Authors:  Steven L A Jeffery
Journal:  Adv Wound Care (New Rochelle)       Date:  2016-10-01       Impact factor: 4.730

3.  Early free flap reconstruction of blast injuries with thermal component.

Authors:  J Bakhach; O Abou Ghanem; D Bakhach; E Zgheib
Journal:  Ann Burns Fire Disasters       Date:  2017-12-31

4.  Dermal regenerative matrix use in burn patients: A systematic review.

Authors:  Katie E Hicks; Minh Nq Huynh; Marc Jeschke; Claudia Malic
Journal:  J Plast Reconstr Aesthet Surg       Date:  2019-08-08       Impact factor: 2.740

5.  Flap decisions and options in soft tissue coverage of the lower limb.

Authors:  Daniel J Jordan; Marco Malahias; Sandip Hindocha; Ali Juma
Journal:  Open Orthop J       Date:  2014-10-31

6.  VRAM flap for an above knee amputation stump.

Authors:  A O Wamalwa; S O Khainga
Journal:  JPRAS Open       Date:  2019-11-13
  6 in total

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