Literature DB >> 23915309

Algorithm for total face and multiorgan procurement from a brain-dead donor.

P S Brazio1, R N Barth, B Bojovic, A H Dorafshar, J P Garcia, E N Brown, S T Bartlett, E D Rodriguez.   

Abstract

Procurement of a facial vascularized composite allograft (VCA) should allow concurrent procurement of all solid organs and ensure their integrity. Because full facial procurement is time-intensive, "simultaneous-start" procurement could entail VCA ischemia over 12 h. We procured a total face osteomyocutaneous VCA from a brain-dead donor. Bedside tracheostomy and facial mask impression were performed preoperative day 1. Solid organ recovery included heart, lungs, liver, kidneys, and pancreas. Facial dissection time was 12 h over 15 h to diminish ischemia while awaiting recipient preparation. Solid organ recovery began at 13.5 h, during midfacial osteotomies, and concluded immediately after facial explantation. Facial thoracic and abdominal teams worked concurrently. Estimated blood loss was 1300 mL, requiring five units of pRBC and two units FFP. Urine output, MAP, pH and PaO2 remained normal. All organs had good postoperative function. We propose an algorithm that allows "face first, concurrent completion" recovery of a complex facial VCA by planning multiple pathways to expedient recovery of vital organs in the event of clinical instability. Beginning the recipient operation earlier may reduce waiting time due to extensive recipient scarring causing difficult dissection. © Copyright 2013 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  Composite tissue transplantation; face transplantation; multiorgan donor; organ and tissue procurement; organ protection and preservation; organ sharing

Mesh:

Year:  2013        PMID: 23915309     DOI: 10.1111/ajt.12382

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  6 in total

1.  Anesthetic Considerations in Facial Transplantation: Experience at NYU Langone Health and Systematic Review.

Authors:  Allyson R Alfonso; Elie P Ramly; Rami S Kantar; William J Rifkin; J Rodrigo Diaz-Siso; Bruce E Gelb; Joseph S Yeh; Mark F Espina; Sudheer K Jain; Greta L Piper; Eduardo D Rodriguez
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-08-17

2.  Successful Recovery and Transplantation of 11 Organs Including Face, Bilateral Upper Extremities, and Thoracic and Abdominal Organs From a Single Deceased Organ Donor.

Authors:  Stefan G Tullius; Bohdan Pomahac; Heung Bae Kim; Matthew J Carty; Simon G Talbot; Helen M Nelson; Francis L Delmonico
Journal:  Transplantation       Date:  2016-10       Impact factor: 4.939

3.  Face transplantation: anesthesia and other organizational considerations.

Authors:  Marie-Eve Bélanger; Daniel E Borsuk; Ariane Clairoux; Louis-Philippe Fortier; Anh Nguyen; Mihai Georgescu; Philippe Richebé; Issam Tanoubi; Olivier Verdonck; Quentin Gobert
Journal:  Can J Anaesth       Date:  2021-02-23       Impact factor: 5.063

Review 4.  Vascularized Composite Allografts: Procurement, Allocation, and Implementation.

Authors:  Axel Rahmel
Journal:  Curr Transplant Rep       Date:  2014

Review 5.  Face transplantation: Anesthetic challenges.

Authors:  Aparna Dalal
Journal:  World J Transplant       Date:  2016-12-24

Review 6.  Face Transplant: Indications, Outcomes, and Ethical Issues-Where Do We Stand?

Authors:  Simone La Padula; Rosita Pensato; Chiara Pizza; Edoardo Coiante; Giovanni Roccaro; Benedetto Longo; Francesco D'Andrea; Francesco Saverio Wirz; Barbara Hersant; Jean Paul Meningaud
Journal:  J Clin Med       Date:  2022-09-28       Impact factor: 4.964

  6 in total

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