Literature DB >> 23914724

Synthesis of highly substituted 4H-pyrido[1,2-a]pyrimidines via a one-pot three-component condensation reaction.

Kai Yang1, Jinbao Xiang, Guochen Bao, Qun Dang, Xu Bai.   

Abstract

A one-pot three-component reaction, involving condensation of 2-aminopyridines, aldehydes, and ketones/aldehydes under trifluoromethanesulfonic acid catalysis, provides rapid access to highly substituted novel 4H-pyrido[1,2-a]pyrimidines.

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Year:  2013        PMID： 23914724     DOI： 10.1021/co400086u

Source DB:  PubMed          Journal:  ACS Comb Sci        ISSN： 2156-8944            Impact factor:   3.784


  5 in total

Review 1.  Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.

Authors:  Simpal Kumari; Dharma Kishore; Sarvesh Paliwal; Rajani Chauhan; Jaya Dwivedi; Aakanksha Mishra
Journal:  Mol Divers       Date:  2015-06-09       Impact factor: 2.943

2.  Discovery of Novel Tricyclic Thiazepine Derivatives as Anti-Drug-Resistant Cancer Agents by Combining Diversity-Oriented Synthesis and Converging Screening Approach.

Authors:  Jinbao Xiang; Zhuoqi Zhang; Yan Mu; Xianxiu Xu; Sigen Guo; Yongjin Liu; Daniel P Russo; Hao Zhu; Bing Yan; Xu Bai
Journal:  ACS Comb Sci       Date:  2016-04-15       Impact factor: 3.784

3.  The Flögel-three-component reaction with dicarboxylic acids - an approach to bis(β-alkoxy-β-ketoenamides) for the synthesis of complex pyridine and pyrimidine derivatives.

Authors:  Mrinal K Bera; Moisés Domínguez; Paul Hommes; Hans-Ulrich Reissig
Journal:  Beilstein J Org Chem       Date:  2014-02-13       Impact factor: 2.883

4.  Design, One Pot Synthesis and Molecular Docking Studies of Substituted-1H-Pyrido[2,1-b] Quinazolines as Apoptosis-Inducing Anticancer Agents.

Authors:  Raju Bathula; Shobha Rani Satla; Ramadevi Kyatham; Kiran Gangarapu
Journal:  Asian Pac J Cancer Prev       Date:  2020-02-01

5.  Naturally Inspired Pyrimidines Analogues for Alzheimer's Disease.

Authors:  Shivani Singh; Meenakshi Dhanawat; Sumeet Gupta; Deepak Kumar; Saloni Kakkar; Anroop Nair; Inderjeet Verma; Prerna Sharma
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363
  5 in total

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