Literature DB >> 23912748

A quantitative model of population dynamics in malaria with drug treatment.

Le Thi Thanh An1, Willi Jäger.   

Abstract

In this paper we build a population dynamics of malaria including drug treatment. By taking into account both sensitive and resistant parasites, we want to see the effect of treatments on resistance phenomenon and prevent it from overspreading. Our main results include a new dynamics model, its mathematical properties which are found through analysis, the determination of unknown parameters with help of a data set for malaria from Burkina Faso and the numerical simulations of the fitted model. Based on these results, treatment strategies to reduce drug resistance can be elaborated.

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Year:  2013        PMID: 23912748     DOI: 10.1007/s00285-013-0716-0

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.259


  8 in total

1.  The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses.

Authors:  W M Watkins; E K Mberu; P A Winstanley; C V Plowe
Journal:  Parasitol Today       Date:  1997-12

2.  A reaction-diffusion system modeling the spread of resistance to an antimalarial drug.

Authors:  Nicolas Bacaer; Cheikh Sokhna
Journal:  Math Biosci Eng       Date:  2005-04       Impact factor: 2.080

Review 3.  Modelling a predictable disaster: the rise and spread of drug-resistantmalaria.

Authors:  I M Hastings; U D'Alessandro
Journal:  Parasitol Today       Date:  2000-08

4.  Plasmodium falciparum parasitaemia described by a new mathematical model.

Authors:  L Molineaux; H H Diebner; M Eichner; W E Collins; G M Jeffery; K Dietz
Journal:  Parasitology       Date:  2001-04       Impact factor: 3.234

Review 5.  The war between the malaria parasite and the immune system: immunity, immunoregulation and immunopathology.

Authors:  K Artavanis-Tsakonas; J E Tongren; E M Riley
Journal:  Clin Exp Immunol       Date:  2003-08       Impact factor: 4.330

6.  Coupling ecology and evolution: malaria and the S-gene across time scales.

Authors:  Zhilan Feng; David L Smith; F Ellis McKenzie; Simon A Levin
Journal:  Math Biosci       Date:  2004-05       Impact factor: 2.144

7.  Malaria: living with drug resistance.

Authors:  A Schapira; P F Beales; M E Halloran
Journal:  Parasitol Today       Date:  1993-05

Review 8.  The role of anti-malarial drugs in eliminating malaria.

Authors:  Nicholas J White
Journal:  Malar J       Date:  2008-12-11       Impact factor: 2.979

  8 in total
  1 in total

Review 1.  The Impact of Antimalarial Use on the Emergence and Transmission of Plasmodium falciparum Resistance: A Scoping Review of Mathematical Models.

Authors:  Aleisha R Brock; Carole A Gibbs; Joshua V Ross; Adrian Esterman
Journal:  Trop Med Infect Dis       Date:  2017-10-15
  1 in total

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