| Literature DB >> 23911314 |
Ryan Rickels1, Ali Shilatifard.
Abstract
Little is known about the molecular machinery that contributes to site-specific copy number variations or how CNVs fit into the chronology of tumor progression. Black et al. (2013) now demonstrate that the overexpression of a histone demethylase induces transient copy gain of specific genomic loci known to harbor proto-oncogenes.Entities:
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Year: 2013 PMID： 23911314 DOI： 10.1016/j.cell.2013.07.010
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582