Literature DB >> 239109

Immediate effects of alkaline infusion in infants with respiratory distress syndrome.

J D Baum, N R Robertson.   

Abstract

Nineteen infants with acidosis associated with RDS were studied following the infusion of: (1) 0.58M (7%) THAM over 30 seconds; (2) molar bicarbonate over 30 seconds; (3) molar bicarbonate over 2 minutes; and (4) molar bicarbonate over 5 minutes. PaC02 fell after THAM; PaC02 rose sharply after bicarbonate and remained elevated 10 minutes after infusion. The pH rose abruptly in all infants and remained significantly elevated 10 minutes after infusion. Pa02 changes were variable; no infant had immediate improvement in Pa02. The changes in osmolality, hematocrit, and colloid osmotic pressure describe the immediate osmotic hemodilution following the infusion of hypertonic base.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 239109     DOI： 10.1016/s0022-3476(75)80597-x

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  4 in total

1.  Management of hyaline membrane disease.

Authors:  N R Roberton
Journal:  Arch Dis Child       Date:  1979-11       Impact factor: 3.791

2.  Disruption of the Golgi zone and inhibition of the conversion of proparathyroid hormone to parathyroid hormone in human parathyroid tissue by tris(hydroxymethyl)aminomethane.

Authors:  D H McGregor; L L Chu; R R MacGregor; D V Cohn
Journal:  Am J Pathol       Date:  1977-06       Impact factor: 4.307

3.  Hyaline membrane disease, alkali, and intraventricular haemorrhage.

Authors:  J S Wigglesworth; I H Keith; D J Girling; S A Slade
Journal:  Arch Dis Child       Date:  1976-10       Impact factor: 3.791

4.  Hypernatraemia as a cause of intracranial haemorrhage.

Authors:  N R Roberton; P Howat
Journal:  Arch Dis Child       Date:  1975-12       Impact factor: 3.791
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.