Literature DB >> 23910891

Fortifying the wall: synthesis, regulation and degradation of bacterial peptidoglycan.

Solmaz Sobhanifar1, Dustin T King, Natalie C J Strynadka.   

Abstract

Growth and maintenance of the protective peptidoglycan cell wall are vital to bacterial growth and morphogenesis. Thus, the relative rate and spatiotemporal control of the synthesis and degradation of this net-like polymer defines bacterial cell shape. In recent years, our understanding of the processes that govern this delicate metabolic balance has improved and should lend insight into how to therapeutically target the system in the future.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID： 23910891     DOI： 10.1016/j.sbi.2013.07.008

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  16 in total

1.  Structural insights into the lipoprotein outer membrane regulator of penicillin-binding protein 1B.

Authors:  Dustin T King; Emilie Lameignere; Natalie C J Strynadka
Journal:  J Biol Chem       Date:  2014-05-07       Impact factor: 5.157

2.  Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B.

Authors:  Dustin T King; Gregory A Wasney; Michael Nosella; Anita Fong; Natalie C J Strynadka
Journal:  J Biol Chem       Date:  2016-11-29       Impact factor: 5.157

3.  Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections.

Authors:  N A Caveney; A Serapio-Palacios; S E Woodward; T Bozorgmehr; G Caballero; M Vuckovic; W Deng; B B Finlay; N C J Strynadka
Journal:  Antimicrob Agents Chemother       Date:  2021-01-20       Impact factor: 5.191

4.  Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.

Authors:  Karthik Sathiyamoorthy; J Vijayalakshmi; Bhramara Tirupati; Lixin Fan; Mark A Saper
Journal:  J Biol Chem       Date:  2017-09-08       Impact factor: 5.157

5.  Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus.

Authors:  J Andrew N Alexander; Som S Chatterjee; Stephanie M Hamilton; Lindsay D Eltis; Henry F Chambers; Natalie C J Strynadka
Journal:  J Biol Chem       Date:  2018-10-26       Impact factor: 5.157

6.  CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution.

Authors:  Nathanael A Caveney; Sean D Workman; Rui Yan; Claire E Atkinson; Zhiheng Yu; Natalie C J Strynadka
Journal:  Nat Commun       Date:  2021-05-13       Impact factor: 14.919

7.  Unwrapping bacteria.

Authors:  Kevin D Young
Journal:  PLoS Genet       Date:  2014-01-02       Impact factor: 5.917

8.  On the reversibility of parasitism: adaptation to a free-living lifestyle via gene acquisitions in the diplomonad Trepomonas sp. PC1.

Authors:  Feifei Xu; Jon Jerlström-Hultqvist; Martin Kolisko; Alastair G B Simpson; Andrew J Roger; Staffan G Svärd; Jan O Andersson
Journal:  BMC Biol       Date:  2016-08-01       Impact factor: 7.431

9.  Functional redundancy of division specific penicillin-binding proteins in Bacillus subtilis.

Authors:  Jad Sassine; Meizhu Xu; Karzan R Sidiq; Robyn Emmins; Jeff Errington; Richard A Daniel
Journal:  Mol Microbiol       Date:  2017-08-29       Impact factor: 3.501

Review 10.  The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets.

Authors:  Yao Liu; Eefjan Breukink
Journal:  Antibiotics (Basel)       Date:  2016-08-26
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