| Literature DB >> 23910468 |
Juliana Bonilla-Velez1, Edmund A Mroz, Rebecca J Hammon, James W Rocco.
Abstract
Oropharyngeal squamous cell carcinoma (OPSCC) originating from human papillomavirus infection has emerged as a new entity in head and neck cancer, defining a subset of patients with distinct carcinogenesis, risk factor profiles, and clinical presentation that show markedly improved survival than patients with classic OPSCC. De-escalation of therapy and identification of relevant biomarkers to aid in patient selection are actively being investigated. This review addresses the implications of these findings in clinical care.Entities:
Keywords: Clinical implications; HPV-positive oropharyngeal cancer; Treatment implications
Mesh:
Substances:
Year: 2013 PMID: 23910468 PMCID: PMC3740406 DOI: 10.1016/j.otc.2013.04.009
Source DB: PubMed Journal: Otolaryngol Clin North Am ISSN: 0030-6665 Impact factor: 3.346