Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Transplantable liver organoids made from only three ingredients.

Literature DB >> 23910079

Transplantable liver organoids made from only three ingredients.

Holger Willenbring¹, Alejandro Soto-Gutierrez.

Abstract

Liver cell therapies using induced pluripotent stem cells (iPSCs) are in development. A recent paper in Nature by Takebe et al. expands the range of liver diseases that could be treated with iPSC-derived hepatocytes by combining them with endothelial and stromal cells to generate organoids that survive and function extrahepatically.

Entities: CellLine Disease Species

Mesh：

Year: 2013 PMID： 23910079 PMCID： PMC3828077 DOI： 10.1016/j.stem.2013.07.014

Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633

10 in total

1. Tissue engineering: creation of long-lasting blood vessels.

Authors: Naoto Koike; Dai Fukumura; Oliver Gralla; Patrick Au; Jeffrey S Schechner; Rakesh K Jain
Journal: Nature Date: 2004-03-11 Impact factor: 49.962

2. Rescue of lethal hepatic failure by hepatized lymph nodes in mice.

Authors: Toshitaka Hoppo; Junji Komori; Rohan Manohar; Donna Beer Stolz; Eric Lagasse
Journal: Gastroenterology Date: 2010-11-09 Impact factor: 22.682

3. Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo.

Authors: Zack Z Wang; Patrick Au; Tong Chen; Ying Shao; Laurence M Daheron; Hao Bai; Melanie Arzigian; Dai Fukumura; Rakesh K Jain; David T Scadden
Journal: Nat Biotechnol Date: 2007-02-25 Impact factor: 54.908

4. Characterization and in vivo testing of mesenchymal stem cells derived from human embryonic stem cells.

Authors: William Gruenloh; Amal Kambal; Claus Sondergaard; Jeannine McGee; Catherine Nacey; Stefanos Kalomoiris; Karen Pepper; Scott Olson; Fernando Fierro; Jan A Nolta
Journal: Tissue Eng Part A Date: 2011-03-04 Impact factor: 3.845

5. The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis.

Authors: Liping Liu; Govardhana Rao Yannam; Taichiro Nishikawa; Toshiyuki Yamamoto; Hesham Basma; Ryotaro Ito; Masaki Nagaya; Joyeeta Dutta-Moscato; Donna B Stolz; Fenghai Duan; Klaus H Kaestner; Yoram Vodovotz; Alejandro Soto-Gutierrez; Ira J Fox
Journal: Hepatology Date: 2012-04-04 Impact factor: 17.425

6. Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix.

Authors: Basak E Uygun; Alejandro Soto-Gutierrez; Hiroshi Yagi; Maria-Louisa Izamis; Maria A Guzzardi; Carley Shulman; Jack Milwid; Naoya Kobayashi; Arno Tilles; Francois Berthiaume; Martin Hertl; Yaakov Nahmias; Martin L Yarmush; Korkut Uygun
Journal: Nat Med Date: 2010-06-13 Impact factor: 53.440

7. Vascularized and functional human liver from an iPSC-derived organ bud transplant.

Authors: Takanori Takebe; Keisuke Sekine; Masahiro Enomura; Hiroyuki Koike; Masaki Kimura; Takunori Ogaeri; Ran-Ran Zhang; Yasuharu Ueno; Yun-Wen Zheng; Naoto Koike; Shinsuke Aoyama; Yasuhisa Adachi; Hideki Taniguchi
Journal: Nature Date: 2013-07-03 Impact factor: 49.962

Review 8. Generation and regeneration of cells of the liver and pancreas.

Authors: Kenneth S Zaret; Markus Grompe
Journal: Science Date: 2008-12-05 Impact factor: 47.728

9. Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice.

Authors: Hisaya Azuma; Nicole Paulk; Aarati Ranade; Craig Dorrell; Muhsen Al-Dhalimy; Ewa Ellis; Stephen Strom; Mark A Kay; Milton Finegold; Markus Grompe
Journal: Nat Biotechnol Date: 2007-07-29 Impact factor: 54.908

10. Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London.

Authors: Juliana Puppi; Stephen C Strom; Robin D Hughes; Sanjay Bansal; Jose V Castell; Ibrahim Dagher; Ewa C S Ellis; Greg Nowak; Bo-Goran Ericzon; Ira J Fox; M José Gómez-Lechón; Chandan Guha; Sanjeev Gupta; Ragai R Mitry; Kazuo Ohashi; Michael Ott; Lola M Reid; Jayanta Roy-Chowdhury; Etienne Sokal; Anne Weber; Anil Dhawan
Journal: Cell Transplant Date: 2012 Impact factor: 4.064