Literature DB >> 23910011

How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response.

Susan J Thorpe1, Richard Stebbings, Lucy Findlay, David Eastwood, Stephen Poole, Robin Thorpe.   

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Year:  2013        PMID： 23910011     DOI： 10.1016/j.cyto.2013.07.009

Source DB:  PubMed          Journal:  Cytokine        ISSN： 1043-4666            Impact factor:   3.861


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  2 in total

Review 1.  Humanized mouse models of immunological diseases and precision medicine.

Authors:  Leonard D Shultz; James Keck; Lisa Burzenski; Sonal Jangalwe; Shantashri Vaidya; Dale L Greiner; Michael A Brehm
Journal:  Mamm Genome       Date:  2019-03-07       Impact factor: 2.957

2.  Cytokine release assays for the prediction of therapeutic mAb safety in first-in man trials--Whole blood cytokine release assays are poorly predictive for TGN1412 cytokine storm.

Authors:  S Vessillier; D Eastwood; B Fox; J Sathish; S Sethu; T Dougall; S J Thorpe; R Thorpe; R Stebbings
Journal:  J Immunol Methods       Date:  2015-05-07       Impact factor: 2.303
  2 in total

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