Literature DB >> 23909403

A new tetrahydrofuran-type lignan with anti-inflammatory activity from Asarum heterotropoides Fr. Schmidt var. mandshuricum.

Jian Huang1, Hui-Qing Wang, Cui Zhang, Guo-Yu Li, Rui-Chao Lin, Jin-Hui Wang.   

Abstract

A new tetrahydrofuran-type lignan, episesaminone (1), was isolated from Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. Its structure was established by spectroscopic techniques (HR-MS, 1D NMR, 2D NMR, and circular dichroism). The anti-inflammatory activity in RAW 264.7 macrophages was carried out on 1 and other eight known compounds, the epimer of 1 (2) and seven known furofurans-type lignan (3-9) obtained from A. heterotropoides Fr. Schmidt var. mandshuricum. Compounds 1, 2, 3, 4, 5, 7, and 9 showed significant anti-inflammatory activity, particularly 50 μM compound 3 inhibited 69.2% NO production compared with the lipopolysaccharide group.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23909403     DOI： 10.1080/10286020.2013.820713

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  7 in total

1.  Effect of the fragrance inhalation of essential oil from Asarum heterotropoides on depression-like behaviors in mice.

Authors:  Hyun-Jung Park; Eun-Ju Lim; Rong Jie Zhao; Sa Rang Oh; Ji Wook Jung; Eun-Mi Ahn; Eun Sook Lee; Jin Suk Koo; Hee Young Kim; Suchan Chang; Hyun Soo Shim; Kwang Joong Kim; Young Seob Gwak; Chae Ha Yang
Journal:  BMC Complement Altern Med       Date:  2015-03-06       Impact factor: 3.659

2.  Chemical Constituents from the Roots and Rhizomes of Asarum heterotropoides var. mandshuricum and the In Vitro Anti-Inflammatory Activity.

Authors:  Yu Jing; Yi-Fan Zhang; Ming-Ying Shang; Guang-Xue Liu; Yao-Li Li; Xuan Wang; Shao-Qing Cai
Journal:  Molecules       Date:  2017-01-13       Impact factor: 4.411

3.  Identification and Quality Evaluation of Raw and Processed Asarum Species Using Microscopy, DNA Barcoding, and Gas Chromatography-Mass Spectrometry.

Authors:  Guangzhe Yao; Wenjuan Ma; Xuhua Huang; Qi Jia; Jiayuan Shen; Yanxu Chang; Huizi Ouyang; Jun He
Journal:  J Anal Methods Chem       Date:  2020-04-13       Impact factor: 2.193

4.  Pharmacokinetic Study of Safrole and Methyl Eugenol after Oral Administration of the Essential Oil Extracts of Asarum in Rats by GC-MS.

Authors:  Yuqi Fan; Dongyue Yang; Xuhua Huang; Guangzhe Yao; Wei Wang; Mengyuan Gao; Xiaohua Jia; Huizi Ouyang; Yanxu Chang; Jun He
Journal:  Biomed Res Int       Date:  2021-03-19       Impact factor: 3.411

5.  New Contributions to Asarum Powder on Immunology Related Toxicity Effects in Lung.

Authors:  Yamin Li; Lintao Han; Chunhua Huang; Wangqiang Dai; Guangyu Tian; Fang Huang; Jingjing Li; Jinwei Liu; Qiong Wang; Zhenxiang Zhou
Journal:  Evid Based Complement Alternat Med       Date:  2018-09-02       Impact factor: 2.629

6.  Bioactive compounds from the roots of Asiasarum heterotropoides.

Authors:  Jun Lee; You Jin Lee; Se-Mi Oh; Jin-Mu Yi; No Soo Kim; Ok-Sun Bang
Journal:  Molecules       Date:  2013-12-23       Impact factor: 4.411

7.  Composition of Asarum heterotropoides var. mandshuricum radix oil from different extraction methods and activities against human body odor-producing bacteria.

Authors:  A S M Tanbirul Haque; Jin Nam Moon; P S Saravana; Adane Tilahun; Byung-Soo Chun
Journal:  J Food Drug Anal       Date:  2016-06-21       Impact factor: 6.157
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.