Literature DB >> 23907191

Transmitting senescence to the cell neighbourhood.

Matthew Hoare1, Masashi Narita.   

Abstract

Senescence, a cell-autonomous tumour suppressor mechanism, also has pro-tumorigenic effects on neighbouring pre-malignant cells through the senescence-associated secretory phenotype (SASP). The SASP is now shown to be regulated by inflammasomes and to induce paracrine senescence in healthy cells, indicating that senescence may also represent a non-cell-autonomous tumour suppressor mechanism linked to innate immunity.

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Year:  2013        PMID： 23907191     DOI： 10.1038/ncb2811

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  14 in total

Review 1.  Inflammasomes in health and disease.

Authors:  Till Strowig; Jorge Henao-Mejia; Eran Elinav; Richard Flavell
Journal:  Nature       Date:  2012-01-18       Impact factor: 49.962

2.  Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.

Authors:  A Krtolica; S Parrinello; S Lockett; P Y Desprez; J Campisi
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-02       Impact factor: 11.205

3.  Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

Authors:  Tae-Won Kang; Tetyana Yevsa; Norman Woller; Lisa Hoenicke; Torsten Wuestefeld; Daniel Dauch; Anja Hohmeyer; Marcus Gereke; Ramona Rudalska; Anna Potapova; Marcus Iken; Mihael Vucur; Siegfried Weiss; Mathias Heikenwalder; Sadaf Khan; Jesus Gil; Dunja Bruder; Michael Manns; Peter Schirmacher; Frank Tacke; Michael Ott; Tom Luedde; Thomas Longerich; Stefan Kubicka; Lars Zender
Journal:  Nature       Date:  2011-11-09       Impact factor: 49.962

4.  Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.

Authors:  Roderik M Kortlever; Paul J Higgins; René Bernards
Journal:  Nat Cell Biol       Date:  2006-07-23       Impact factor: 28.824

Review 5.  Pyroptosis: host cell death and inflammation.

Authors:  Tessa Bergsbaken; Susan L Fink; Brad T Cookson
Journal:  Nat Rev Microbiol       Date:  2009-02       Impact factor: 60.633

6.  Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network.

Authors:  Arturo V Orjalo; Dipa Bhaumik; Bridget K Gengler; Gary K Scott; Judith Campisi
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-28       Impact factor: 11.205

7.  Chemokine signaling via the CXCR2 receptor reinforces senescence.

Authors:  Juan C Acosta; Ana O'Loghlen; Ana Banito; Maria V Guijarro; Arnaud Augert; Selina Raguz; Marzia Fumagalli; Marco Da Costa; Celia Brown; Nikolay Popov; Yoshihiro Takatsu; Jonathan Melamed; Fabrizio d'Adda di Fagagna; David Bernard; Eva Hernando; Jesús Gil
Journal:  Cell       Date:  2008-06-13       Impact factor: 41.582

8.  Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Authors:  Jean-Philippe Coppé; Christopher K Patil; Francis Rodier; Yu Sun; Denise P Muñoz; Joshua Goldstein; Peter S Nelson; Pierre-Yves Desprez; Judith Campisi
Journal:  PLoS Biol       Date:  2008-12-02       Impact factor: 8.029

9.  Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

Authors:  Narendra Wajapeyee; Ryan W Serra; Xiaochun Zhu; Meera Mahalingam; Michael R Green
Journal:  Cell       Date:  2008-02-08       Impact factor: 41.582

10.  A complex secretory program orchestrated by the inflammasome controls paracrine senescence.

Authors:  Juan Carlos Acosta; Ana Banito; Torsten Wuestefeld; Athena Georgilis; Peggy Janich; Jennifer P Morton; Dimitris Athineos; Tae-Won Kang; Felix Lasitschka; Mindaugas Andrulis; Gloria Pascual; Kelly J Morris; Sadaf Khan; Hong Jin; Gopuraja Dharmalingam; Ambrosius P Snijders; Thomas Carroll; David Capper; Catrin Pritchard; Gareth J Inman; Thomas Longerich; Owen J Sansom; Salvador Aznar Benitah; Lars Zender; Jesús Gil
Journal:  Nat Cell Biol       Date:  2013-06-16       Impact factor: 28.824
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  33 in total

1.  Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

Authors:  Daniel M Waldera Lupa; Faiza Kalfalah; Kai Safferling; Petra Boukamp; Gereon Poschmann; Elena Volpi; Christine Götz-Rösch; Francoise Bernerd; Laura Haag; Ulrike Huebenthal; Ellen Fritsche; Fritz Boege; Niels Grabe; Julia Tigges; Kai Stühler; Jean Krutmann
Journal:  J Invest Dermatol       Date:  2015-03-27       Impact factor: 8.551

2.  Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21(waf-1).

Authors:  Souneek Chakraborty; Reyaz Ur Rasool; Sunil Kumar; Debasis Nayak; Bilal Rah; Archana Katoch; Hina Amin; Asif Ali; Anindya Goswami
Journal:  Age (Dordr)       Date:  2016-05-31

Review 3.  Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence.

Authors:  Paula R Barros; Tiago J Costa; Eliana H Akamine; Rita C Tostes
Journal:  Front Aging       Date:  2021-09-08

4.  Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs).

Authors:  Thomas J Bartosh; Mujib Ullah; Suzanne Zeitouni; Joshua Beaver; Darwin J Prockop
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-03       Impact factor: 11.205

5.  Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK.

Authors:  Paul A Toste; Andrew H Nguyen; Brian E Kadera; Mindy Duong; Nanping Wu; Irmina Gawlas; Linh M Tran; Mihir Bikhchandani; Luyi Li; Sanjeet G Patel; David W Dawson; Timothy R Donahue
Journal:  Mol Cancer Res       Date:  2016-03-15       Impact factor: 5.852

Review 6.  Inside and out: the activities of senescence in cancer.

Authors:  Pedro A Pérez-Mancera; Andrew R J Young; Masashi Narita
Journal:  Nat Rev Cancer       Date:  2014-07-17       Impact factor: 60.716

7.  Dystrophic microglia are associated with neurodegenerative disease and not healthy aging in the human brain.

Authors:  Ryan K Shahidehpour; Rebecca E Higdon; Nicole G Crawford; Janna H Neltner; Eseosa T Ighodaro; Ela Patel; Douglas Price; Peter T Nelson; Adam D Bachstetter
Journal:  Neurobiol Aging       Date:  2021-01-07       Impact factor: 4.673

Review 8.  Senescent Microglia: The Key to the Ageing Brain?

Authors:  Eleanor K Greenwood; David R Brown
Journal:  Int J Mol Sci       Date:  2021-04-22       Impact factor: 5.923

9.  Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age.

Authors:  Fabiola Marino; Mariangela Scalise; Nadia Salerno; Luca Salerno; Claudia Molinaro; Donato Cappetta; Michele Torella; Marta Greco; Daniela Foti; Ferdinando C Sasso; Pasquale Mastroroberto; Antonella De Angelis; Georgina M Ellison-Hughes; Maurilio Sampaolesi; Marcello Rota; Francesco Rossi; Konrad Urbanek; Bernardo Nadal-Ginard; Daniele Torella; Eleonora Cianflone
Journal:  Diabetes       Date:  2022-05-01       Impact factor: 9.337

10.  Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells.

Authors:  Valentina Minieri; Silvia Saviozzi; Giovanna Gambarotta; Marco Lo Iacono; Lisa Accomasso; Elisa Cibrario Rocchietti; Clara Gallina; Valentina Turinetto; Claudia Giachino
Journal:  J Cell Mol Med       Date:  2015-01-26       Impact factor: 5.310
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