CONTEXT: Waterpipe tobacco smoking (WTS) has gained popularity, but its physiologic effects have not been extensively studied: rather, studies have focused on WTS's chronic effects or have evaluated limited respiratory/cardiac parameters. OBJECTIVE: We sought to characterize in a more detailed manner the acute effects of WTS on lung function and exercise capacity. METHOD: We recruited 24 healthy WTS males. We used a pilot single-group pre-test (abstained from WTS for ≥48 h) post-test (within 0.5 h of a 45-min WTS session) design. We performed spirometry, diffusing lung capacity and time-limited CPE testing (CPET; cycloergometer; 2-min 20-Watt warm-up and 25-Watt increase every 2-min for 10 min). RESULTS: Mean age was 20.4 years; Post-WTS, the following significant changes were observed: CO level increased from 3.7 ppm to 24.4; oxygen consumption decreased (from 1.86 L/min to 1.7); baseline respiratory rate increased (from 17.7 breath/min to 19.7); forced expiratory flow over the middle half of the forced vital capacity decreased (from 5.51 L to 5.29); and perceived exertion (measured by Borg scale) at mid and peak exercise increased. Baseline resting systolic blood pressure, pulse pressure, and pulse pressure product increased post-WTS (from 118.9 mmHg to 129.2; from 45.3 mmHg to 55.6; and from 9.9 mmHg/min to 11.1 post-WTS, respectively). During exercise, a decrease in oxygen pulse was observed post-WTS (from 10.89 ml/beat to 9.97), while the heart rate-oxygen consumption relationship increased post-WTS (from 3.52 beats/ml/kg to 3.91). CONCLUSION: Acute WTS appears to induce impairment in lung function and exercise capacity. Larger studies are warranted to further characterize the nature and extent of such impairment.
CONTEXT: Waterpipe tobacco smoking (WTS) has gained popularity, but its physiologic effects have not been extensively studied: rather, studies have focused on WTS's chronic effects or have evaluated limited respiratory/cardiac parameters. OBJECTIVE: We sought to characterize in a more detailed manner the acute effects of WTS on lung function and exercise capacity. METHOD: We recruited 24 healthy WTS males. We used a pilot single-group pre-test (abstained from WTS for ≥48 h) post-test (within 0.5 h of a 45-min WTS session) design. We performed spirometry, diffusing lung capacity and time-limited CPE testing (CPET; cycloergometer; 2-min 20-Watt warm-up and 25-Watt increase every 2-min for 10 min). RESULTS: Mean age was 20.4 years; Post-WTS, the following significant changes were observed: CO level increased from 3.7 ppm to 24.4; oxygen consumption decreased (from 1.86 L/min to 1.7); baseline respiratory rate increased (from 17.7 breath/min to 19.7); forced expiratory flow over the middle half of the forced vital capacity decreased (from 5.51 L to 5.29); and perceived exertion (measured by Borg scale) at mid and peak exercise increased. Baseline resting systolic blood pressure, pulse pressure, and pulse pressure product increased post-WTS (from 118.9 mmHg to 129.2; from 45.3 mmHg to 55.6; and from 9.9 mmHg/min to 11.1 post-WTS, respectively). During exercise, a decrease in oxygen pulse was observed post-WTS (from 10.89 ml/beat to 9.97), while the heart rate-oxygen consumption relationship increased post-WTS (from 3.52 beats/ml/kg to 3.91). CONCLUSION: Acute WTS appears to induce impairment in lung function and exercise capacity. Larger studies are warranted to further characterize the nature and extent of such impairment.
Authors: Omar F Khabour; Karem H Alzoubi; Tuqa M Abu Thiab; Belal A Al-Husein; Thomas Eissenberg; Alan Louis Shihadeh Journal: Inhal Toxicol Date: 2015-10-20 Impact factor: 2.724
Authors: Aruni Bhatnagar; Wasim Maziak; Thomas Eissenberg; Kenneth D Ward; George Thurston; Brian A King; Erin L Sutfin; Caroline O Cobb; Merlyn Griffiths; Larry B Goldstein; Mary Rezk-Hanna Journal: Circulation Date: 2019-05-07 Impact factor: 29.690
Authors: Ahmed B Alarabi; Zubair A Karim; Jean E Montes Ramirez; Keziah R Hernandez; Patricia A Lozano; José O Rivera; Fatima Z Alshbool; Fadi T Khasawneh Journal: Arterioscler Thromb Vasc Biol Date: 2020-01-16 Impact factor: 8.311
Authors: Majed M Masadeh; Emad I Hussein; Karem H Alzoubi; Omar Khabour; Muhamad Ali K Shakhatreh; Mahmoud Gharaibeh Journal: Int J Environ Res Public Health Date: 2015-05-13 Impact factor: 3.390
Authors: Sultan Ayoub Meo; Khaled Ahmed AlShehri; Bader Bandar AlHarbi; Omar Rayyan Barayyan; Abdulrahman Salem Bawazir; Omar Abdulmohsin Alanazi; Ahmed Raad Al-Zuhair Journal: Int J Environ Res Public Health Date: 2014-09-17 Impact factor: 3.390