Literature DB >> 23905141

MRI sequence and characteristic features in 'giant cell tumor' of clivus.

Ajit Mahale1, Dhananjaya K V N, Muralidhar Pai, Vinaya Poornima, Kausalya Kumari Sahu.   

Abstract

Giant cell tumours of the clivus are rare. These tumours present in the second and third decades of life and they are slightly more frequent in women than in men. We are presenting a case of a 20 years young patient who came with the complaints of headache, retro-orbital pain and recurrent transient bleeding from the nose since two and half months. MRI of the brain with contrast was done and its features were suggestive of a Giant cell tumour of the clivus. A transnasal endoscopic biopsy was done under general anaesthesia and the histopathology report suggested that the features were of a giant cell tumour. Excision of the mass was done by Transnasal endoscopy. Post operatively, the patient did not recover from the lateral rectus palsy which was there on the right side. The patient was discharged with an advice of a follow up and radiotherapy. Radiation therapy and chemotherapy may be effective as adjuvant treatments. Even though a recurrence usually occurs within 4 years of the initial treatment, these patients will need to be carefully followed for the remainder of their lives.

Entities:  

Keywords:  Clivus; MRI; Osteogenic; Tumour

Year:  2013        PMID: 23905141      PMCID: PMC3708236          DOI: 10.7860/JCDR/2013/2725.3021

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  16 in total

1.  Giant cell reparative granuloma of the skull base mimicking an intracranial tumor. Case report and review of the literature.

Authors:  P Ciappetta; M Salvati; C Bernardi; A Raco; N Di Lorenzo
Journal:  Surg Neurol       Date:  1990-01

Review 2.  Giant cell tumor of the sphenoid bone: long-term follow-up of two cases after chemotherapy.

Authors:  M Yamamoto; T Fukushima; S Sakamoto; M Tomonaga
Journal:  Surg Neurol       Date:  1998-05

3.  Giant cell tumor of the sphenoid bone. A case report and review of the literature.

Authors:  W E Emley
Journal:  Arch Otolaryngol       Date:  1971-10

4.  Giant cell tumors of the sphenoid bone.

Authors:  J D Geissger; E B Siqueira; E R Ross
Journal:  J Neurosurg       Date:  1970-06       Impact factor: 5.115

5.  Giant-cell tumor of bone. An analysis of two hundred and eighteen cases.

Authors:  R R Goldenberg; C J Campbell; M Bonfiglio
Journal:  J Bone Joint Surg Am       Date:  1970-06       Impact factor: 5.284

6.  Giant cell tumour of the sphenoid bone with coincidental galactorrhoea--a case report.

Authors:  A A Kemeny; F Afshar
Journal:  Br J Neurosurg       Date:  1990       Impact factor: 1.596

7.  Giant-cell tumor of bone with pulmonary metastases.

Authors:  F Bertoni; D Present; W F Enneking
Journal:  J Bone Joint Surg Am       Date:  1985-07       Impact factor: 5.284

8.  Generalised giant-cell tumour of bone: successful treatment of pulmonary metastases with interferon alpha, a case report.

Authors:  U Kaiser; K Neumann; K Havemann
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

9.  Giant-cell tumor of the sphenoid bone. Review of 10 cases.

Authors:  J T Wolfe; B W Scheithauer; D C Dahlin
Journal:  J Neurosurg       Date:  1983-08       Impact factor: 5.115

10.  Giant cell tumor of the skull.

Authors:  F Bertoni; K K Unni; J W Beabout; M J Ebersold
Journal:  Cancer       Date:  1992-09-01       Impact factor: 6.860

View more
  2 in total

1.  Unresectable Clival Giant Cell Tumor, Tumor Control With Denosumab After Relapse: A Case Report and Systematic Review of the Literature.

Authors:  Maria Grazia Pionelli; Sebastian D Asaftei; Elisa Tirtei; Anna Campello; Gianpaolo Di Rosa; Franca Fagioli
Journal:  J Pediatr Hematol Oncol       Date:  2022-05-09       Impact factor: 1.170

Review 2.  The identification of H3F3A mutation in giant cell tumour of the clivus and the histological diagnostic algorithm of other clival lesions permit the differential diagnosis in this location.

Authors:  Federica Scotto di Carlo; Giuseppina Divisato; Maurizio Iacoangeli; Teresa Esposito; Fernando Gianfrancesco
Journal:  BMC Cancer       Date:  2018-04-02       Impact factor: 4.430

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.