Ananthalakshmi Vijayakumar1. 1. Assistant Professor, Department of Pathology, Sree Balaji Medical College and Hospital, Bharath University , Chromepet, Chennai-600044, India .
Abstract
BACKGROUND: The present study was done to evaluate the status of intraoperative cytology as a diagnostic and supportive investigation for ovarian tumours. MATERIAL AND METHODS: The present study was conducted in the Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India during a time span of 13 months (June 2011 to June 2012). A prospective investigation was performed on 50 cases of suspected ovarian neoplasms. Imprint smears were made intraoperatively from fresh samples from various representative areas, and they were immediately fixed in 95% ethyl alcohol and stained with the haematoxylin and eosin stain. The results were compared with the final histopathological diagnoses in each case. RESULTS: There were 20 benign lesions, 4 borderline epithelial neoplasms and 26 malignant tumours according to the final histopathological diagnosis. The overall diagnostic accuracy of imprint cytology has been satisfactory, with those of 90% of the cases correlating with the final diagnoses. Characteristic cytological patterns were noted in various surface epithelial, sex cord stromal and germ cell tumours. CONCLUSION: Imprint cytology can be used as an adjunct to histopathology for a rapid and an early diagnosis in the operation theatre, particularly in developing countries like ours, where the facility of frozen sections is often not available, since a rapid preliminary diagnosis may help in the surgical management planning.
BACKGROUND: The present study was done to evaluate the status of intraoperative cytology as a diagnostic and supportive investigation for ovarian tumours. MATERIAL AND METHODS: The present study was conducted in the Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India during a time span of 13 months (June 2011 to June 2012). A prospective investigation was performed on 50 cases of suspected ovarian neoplasms. Imprint smears were made intraoperatively from fresh samples from various representative areas, and they were immediately fixed in 95% ethyl alcohol and stained with the haematoxylin and eosin stain. The results were compared with the final histopathological diagnoses in each case. RESULTS: There were 20 benign lesions, 4 borderline epithelial neoplasms and 26 malignant tumours according to the final histopathological diagnosis. The overall diagnostic accuracy of imprint cytology has been satisfactory, with those of 90% of the cases correlating with the final diagnoses. Characteristic cytological patterns were noted in various surface epithelial, sex cord stromal and germ cell tumours. CONCLUSION: Imprint cytology can be used as an adjunct to histopathology for a rapid and an early diagnosis in the operation theatre, particularly in developing countries like ours, where the facility of frozen sections is often not available, since a rapid preliminary diagnosis may help in the surgical management planning.
Entities:
Keywords:
Cytology; Imprint cytology; Intra operative; Ovarian tumors
Authors: V Shidham; D Gupta; L M Galindo; M Haber; C Grotkowski; P Edmonds; S J Subichin; V George; J England Journal: Diagn Cytopathol Date: 2000-08 Impact factor: 1.582
Authors: Nithya D G Ratnavelu; Andrew P Brown; Susan Mallett; Rob J P M Scholten; Amit Patel; Christina Founta; Khadra Galaal; Paul Cross; Raj Naik Journal: Cochrane Database Syst Rev Date: 2016-03-01